中西医结合肝病杂志2025，Vol.35Issue(9)：1074-1077,4.DOI:10.3969/j.issn.1005-0264.2025.009.004
代谢相关脂肪性肝病患者的营养风险与肝脏硬度的相关性研究
Correlation between nutritional risk and LSM in individuals suffering from MAFLD
摘要
Abstract
Objective:To investigate the correlation between nutritional risk and liver stiffness measurement in patients with metabolic-associated fatty liver disease(MAFLD).Methods:A total of 103 patients with MAFLD were selected from the Department of Gastroenterology,Puren Hospital affiliated with Wuhan University of Science and Technology.Based on the criteria of the Nutritional Risk Screening 2002(NRS 2002),the patients were categorized into two groups:a nutritional risk group(scoring three points or above)and a non-nutritional risk group(scoring below three points).The liver stiffness measurement(LSM)and controlled attenuation parameter(CAP)of patients were measured by transient elastography,and compared with the NRS2002 score,body mass index(BMI),and laboratory test indexes.Results:There were significant statistical differences in patients'age,body mass index(BMI),triglyceride(TG),total cholesterol(TC),liver stiffness measurement(LSM),albumin(ALB),and hemoglobin(HGB)between the two groups(P<0.05).LSM values of the nutritional risk group and the non-nutritional risk group were 14.55(13.2,16.7)kPa and 8.4(6.2,12.4)kPa,respectively.The measurement of LSM was notably elevated in the nutritional risk group compared to the non-nutritional risk group,with a statistically significant difference(P<0.05).According to logistic regression analysis,an increase in LSM corresponds to a higher likelihood of patients encountering nutritional risks(OR=1.010,95%CI:0.839-1.216).The ROC curve(Receiver Operating Characteristic Curve)was employed to assess the diagnostic value of liver stiffness measurement compared to other nutritional indicators.The area under the ROC curve of LSM was 0.855,which was more significant than other traditional indicators.Conclusion:The occurrence of nutritional risk in patients with MAFLD is closely related to liver stiffness.Among many nutritional assessment methods,LSM shows better diagnostic efficiency.关键词
代谢相关脂肪性肝病/营养风险/瞬时弹性成像技术/肝脏硬度值Key words
metabolic-associated fatty liver disease/nutritional risk/transient elastography/liver stiffness measurement分类
医药卫生引用本文复制引用
陈繁,方向明..代谢相关脂肪性肝病患者的营养风险与肝脏硬度的相关性研究[J].中西医结合肝病杂志,2025,35(9):1074-1077,4.基金项目
中国金属学会冶金安全与健康分会健康卫生科研项目(No.jkws202318) （No.jkws202318）
