阿尔茨海默病及相关病2025，Vol.8Issue(5)：334-341,8.DOI:10.3969/j.issn.2096-5516.2025.05.008
阿尔茨海默病患者衰弱检出率的Meta分析
Meta-analysis of the prevalence of frailty in Alzheimer's patients
摘要
Abstract
Objective:To conduct a meta-analysis on the incidence of frailty in patients with Alzheimer's Disease(AD),in order to provide a scientific basis for the prevention of frailty in AD patients.Methods:By systematically searching CNKI,Wanfang,VIP Chinese databases,PubMed,Web of Science,Embase and Cochrane Library English databases,the epidemiological evidence of the incidence of frailness in AD patients was comprehensively obtained.The literature search period was set from the establishment of the database to March 10,2025,and literature screening,data extraction and bias risk assessment were carried out by two researchers respectively.Statistical software Stata14.0 was used to conduct a meta-analysis of the included studies.Results:Thirteen studies were included,covering 2806 patients with Alzheimer's disease,and the analysis suggested an overall incidence of frailty of 34%(95%CI:27%～41%).Study area,measurement tool,study time,sample size and other factors have an impact on the incidence of frailty in patients with Alzheimer's disease.Conclusion:The incidence of frailties in patients with Alzheimer's disease is high.Attention should be paid to frailties in patients with Alzheimer's disease,and early detection and intervention measures should be taken to reduce the occurrence of frailties in this population.关键词
阿尔茨海默病/衰弱/检出率/Meta分析Key words
Alzheimer's disease/Frailty/Prevalence/Meta-analysis分类
医药卫生引用本文复制引用
龙泉滋,廖喜琳,苏幼美,周辰鲁,范葵钰..阿尔茨海默病患者衰弱检出率的Meta分析[J].阿尔茨海默病及相关病,2025,8(5):334-341,8.基金项目
2023年度广西职业教育教学改革研究重点项目:虚拟仿真技术数字赋能的养老护理人才培养模式研究与实践(GXZZJG2023A055) （GXZZJG2023A055）
广西壮族自治区中医院管理局自筹经费科研课题(GXZYZ20210364) （GXZYZ20210364）
