材料科学与工程学报2025，Vol.43Issue(4)：525-530,6.DOI:10.14136/j.cnki.issn1673-2812.2025.04.003
超声穿颅声阻抗梯度渐变匹配层材料的设计与优化
Design and Optimization of Gradient Acoustic Impedance Matching Layer Materials for Transcranial Ultrasound
摘要
Abstract
Transcranial ultrasound imaging holds significant clinical value due to its non-ionizing nature and portability.However,the acoustic impedance mismatch between the skull and soft tissue results in strong ultrasound reflections,severely limiting effective penetration for intracranial tissue and blood flow imaging.To address this challenge,this study designed and optimized the material parameters of a gradient acoustic impedance matching layer for transcranial ultrasound applications.This matching layer significantly enhances the sound intensity transmission coefficient across a broad frequency range(1-2 MHz),comparable to a continuous impedance matching layer.The proposed layer effectively reduces target shape distortion and enhances image signal quality.In addition,the simulation results of the curved skull model show excellent practical prospects of the gradient matching layers.This study provides important guidance for the experimental preparation of the gradient acoustic impedance matching layer for ultrasonic transcranial applications,and lays a theoretical foundation for the optimization and application of the matching layer.关键词
声阻抗梯度渐变/超声穿颅/有限元分析Key words
Gradient acoustic impedance/Transcranial ultrasound/Finite element analysis分类
医药卫生引用本文复制引用
易振宇,陈洁,陈恬甜,吴勇军,洪子健,黄玉辉..超声穿颅声阻抗梯度渐变匹配层材料的设计与优化[J].材料科学与工程学报,2025,43(4):525-530,6.基金项目
国家重点研发计划课题项目(2021YFB3801802) （2021YFB3801802）
