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法医转录组学技术在体液斑迹组织来源推断中的应用

白一帆 赵禾苗 陈静 刘洪迪 杨瑞琴 王冲

法医学杂志2025,Vol.41Issue(3):260-266,7.
法医学杂志2025,Vol.41Issue(3):260-266,7.DOI:10.12116/j.issn.1004-5619.2024.540306

法医转录组学技术在体液斑迹组织来源推断中的应用

Application of Forensic Transcriptomics in the Identification of Tissue Origin of Body Fluid Stains

白一帆 1赵禾苗 2陈静 2刘洪迪 2杨瑞琴 3王冲2

作者信息

  • 1. 中国人民公安大学侦查学院,北京 100038||公安部鉴定中心 法医遗传学公安部重点实验室,北京 100038
  • 2. 公安部鉴定中心 法医遗传学公安部重点实验室,北京 100038
  • 3. 中国人民公安大学侦查学院,北京 100038
  • 折叠

摘要

Abstract

The inference of tissue origin of body fluid stains is crucial for case investigation and court proceedings.However,traditional methods for identification of body fluid stains,such as morpho-logical,chemical,and immunoassay identifications have certain limitations,and there is an urgent need for more efficient methods for confirmatory experiments.In recent years,the rapid development of tran-scriptomics technology has provided new means for the identification of tissue origin of body fluid stains.Different types of RNA in the transcriptome have their own advantages.This paper elaborates in detail on the application of different types of RNA,such as mRNA,miRNA,circRNA,lncRNA,piRNA and microbial transcriptomics in body fluid identification,and summarizes their respective ad-vantages and limitations,in order to provide a reference for related research.

关键词

法医遗传学/转录组学/体液斑迹/组织来源推断/综述

Key words

forensic genetics/transcriptomics/body fluid stains/tissue origin identification/review

分类

医药卫生

引用本文复制引用

白一帆,赵禾苗,陈静,刘洪迪,杨瑞琴,王冲..法医转录组学技术在体液斑迹组织来源推断中的应用[J].法医学杂志,2025,41(3):260-266,7.

基金项目

中央级公益性科研院所资助项目(2023JB005) (2023JB005)

法医学杂志

OA北大核心

1004-5619

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