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单次根管疏通填充对牙体牙髓病患者填充效果、龈沟液IL-1β、IL-17A、IL-35水平的影响

于昕琦 潘裕兴 鲁译暄

广州医药2025,Vol.56Issue(8):1069-1073,5.
广州医药2025,Vol.56Issue(8):1069-1073,5.DOI:10.20223/j.cnki.1000-8535.2025.08.008

单次根管疏通填充对牙体牙髓病患者填充效果、龈沟液IL-1β、IL-17A、IL-35水平的影响

Effects of one-time root canal dredging and filling on filling effect and levels of IL-1β,IL-17A and IL-35 in gingival crevicular fluid in patients with endodontic disease

于昕琦 1潘裕兴 1鲁译暄2

作者信息

  • 1. 天津市人民医院口腔科(天津 300121)
  • 2. 北京大学口腔医学院(北京 100081)
  • 折叠

摘要

Abstract

Objective To explore the effects of one-time root canal dredging and filling on the filling effect and gingival crevicular fluid inflammation indexes in patients with endodontic disease.Methods A total of 84 cases of endodontic patients admitted to the Tianjin People's Hospital from August 2023 to February 2024 were chosen and separated into the control group(n=42,multiple-time root canal dredging and filling)and the observation group(n=42,one-time root canal dredging and filling)by random number table method.The filling effect,therapeutic effect,gingival creval fluid inflammation indicators,oral health and function indicators,and complications were compared.Results The underfilling,accurate filling and overfilling showed no significant difference between the two groups(χ2=0.262,1.615,0.512,P=0.608,0.203,0.474).The total effective rate of observation group was 97.62%,higher than that of control group 80.95%(χ2=6.098,P=0.014).After treatment,levels of interleukin(IL)-1β,IL-17A,IL-35 and tumor necrosis factor-α in gingival crevicular fluid of observation group were lower(t=3.271、3.028、2.699、2.968,P=0.002、0.003、0.008、0.004).After treatment,the sulcus bleeding index and gingival index of the observation group were lower,and the biting force and mastication efficiency were higher(t=2.311、2.686、2.262、2.776,P=0.023、0.009、0.026、0.007).The complication rate in the observation group was 4.76%,lower than that in the control group 21.43%(χ2=5.126,P=0.024).Conclusions A one-time root canal dredging and filling treatment for endodontic diseases can ensure proper filling effect,achieve good therapeutic effect,reduce gingival crevicular fluid inflammation,promote oral health and function improvement,with fewer complications,high safety,which is worthy of promotion.

关键词

牙体牙髓病/单次根管疏通填充/填充效果/龈沟液/并发症

Key words

endodontic disease/one-time root canal dredging and filling/filling effect/gingival crevicular fluid/complication

引用本文复制引用

于昕琦,潘裕兴,鲁译暄..单次根管疏通填充对牙体牙髓病患者填充效果、龈沟液IL-1β、IL-17A、IL-35水平的影响[J].广州医药,2025,56(8):1069-1073,5.

广州医药

1000-8535

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