海南医科大学学报2025，Vol.31Issue(17)：1353-1360,8.DOI:10.13210/j.cnki.jhmu.20250428.001
丘脑底核脑深部电刺激术对帕金森病合并冻结步态的研究进展
Research progress of deep brain stimulation in subthalamic nucleus for Parkinson's disease complicated with freezing of gait
摘要
Abstract
Freezing of gait(FOG)is a common movement symptom of Parkinson's disease(PD),which often leads to falls and fractures,seriously affecting the quality of life of PD patients.The effect of subthalamic nucleus deep brain stimulation(STN-DBS)on some motor symptoms of PD is clear,but the effect on FOG is inconclusive.In this paper,the epidemiological characteristics and pathogenesis of PD combined with FOG and the effect of STN-DBS on PD were discussed.This paper pro-vides an overview of the epidemiological features,pathogenesis and influencing factors of PD combined with FOG,the efficacy and treatment mechanism of STN-DBS on PD combined with FOG,the position of electrode contacts during STN-DBS,and the influence of postoperative programme control strategies and drug adjustments on PD combined with FOG,with the aim of provid-ing references for in-depth studies related to PD combined with FOG.关键词
帕金森病/冻结步态/丘脑底核/脑深部电刺激术Key words
Parkinson′s disease/Freezing of gait/Subthalamic nucleus/Deep brain stimulation分类
医药卫生引用本文复制引用
胡佳豪,李庆志,莫斌,王帜,罗凯,李俊驹..丘脑底核脑深部电刺激术对帕金森病合并冻结步态的研究进展[J].海南医科大学学报,2025,31(17):1353-1360,8.基金项目
This study was supported by the Hainan Provincial Natural Science Foundation High-evel Talent Project(821RC682) 海南省自然科学基金高层次人才项目(821RC682) （821RC682）
