国际神经病学神经外科学杂志2025，Vol.52Issue(4)：1-5,5.DOI:10.16636/j.cnki.jinn.1673-2642.2025.04.001
胶质瘤患者术后影响生存的因素及其评估模型
Influencing factors for postoperative survival of patients with glioma and establishment of a prognostic model
摘要
Abstract
Objective To investigate the influencing factors for postoperative survival of patients with glioma,to establish an accurate prognostic model,and to provide a reliable basis for clinical treatment decision-making and prognostic evaluation.Methods Related clinical data were collected from the patients with glioma,including age,sex,tumor location,pathological classification,extent of surgical resection,postoperative radiotherapy,and chemotherapy.The methods for statistical analysis were used to determine the risk factors for postoperative survival of patients.Based on these factors,machine learning algorithms were used to establish a prognostic model,and internal and external validations were performed for comprehensive evaluation.Results The comprehensive analysis showed that age,pathological classification,extent of surgical resection,postoperative radiotherapy,and chemotherapy were associated with the postoperative survival time of patients.The multivariate analysis further revealed that pathological classification,extent of surgical resection,and postoperative radiotherapy were risk factors for postoperative survival of patients.The prognostic model established had excellent predictive performance and could accurately evaluate the prognosis of patients.Conclusions Pathological classification,extent of surgical resection,and postoperative radiotherapy are important influencing factors for postoperative survival of patients with glioma.The prognostic model established in this study provides a scientific prognostic assessment tool for clinicians.关键词
胶质瘤/影响因素/预后模型/生存分析Key words
glioma/influencing factors/prognostic model/survival analysis分类
医药卫生引用本文复制引用
刘桠菲,周霖,郑天元..胶质瘤患者术后影响生存的因素及其评估模型[J].国际神经病学神经外科学杂志,2025,52(4):1-5,5.基金项目
河南省科技攻关计划项目(242102311261). （242102311261）
