国际神经病学神经外科学杂志2025，Vol.52Issue(4)：39-45,7.DOI:10.16636/j.cnki.jinn.1673-2642.2025.04.007
磁感应热疗在脑胶质瘤治疗中的研究进展
Research advances in magnetic induction hyperthermia in the treatment of glioma
王垚 1张焕芝 2彭华康1
作者信息
- 1. 清华大学工程物理系,北京 100084
- 2. 北京大学人民医院妇产科,北京 100044
- 折叠
摘要
Abstract
Magnetic induction hyperthermia(MIH)is an emerging physical therapy regimen,and it can achieve selective thermal damage to tumor cells through targeted delivery of magnetic nanoparticles to tumor sites,followed by activation of these particles to generate heat under an external alternating magnetic field.Studies have shown that the advantage of MIH lies in its ability to precisely control the heating area,reduce damage to surrounding normal tissue,activate heat shock protein and immune response,and enhance the anti-tumor effect.This article reviews the research advances in MIH in animal experiments and clinical trials.The analysis of existing literature shows that MIH treatment has shown great potential in improving the survival time and quality of life of patients,but further studies are still needed to address the issues such as selection of treatment parameters,safety assessment,and long-term efficacy monitoring.With the continuous advances in material science and biomedical engineering,MIH is expected to become an important component of the comprehensive treatment strategy for glioma.关键词
磁感应热疗/胶质瘤/金属纳米颗粒Key words
magnetic induction hyperthermia/glioma/metallic nanoparticles分类
医药卫生引用本文复制引用
王垚,张焕芝,彭华康..磁感应热疗在脑胶质瘤治疗中的研究进展[J].国际神经病学神经外科学杂志,2025,52(4):39-45,7.
