国际神经病学神经外科学杂志2025，Vol.52Issue(4)：53-60,8.DOI:10.16636/j.cnki.jinn.1673-2642.2025.04.009
动脉瘤性蛛网膜下腔出血后迟发性脑缺血病理生理学机制的研究现状
Current status of research on the pathophysiological mechanisms of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage
摘要
Abstract
Aneurysmal subarachnoid hemorrhage(aSAH)is the third most critical neurological condition,following cerebral infarction and intracerebral hemorrhage.Its complication,delayed cerebral ischemia(DCI),is a significant cause of prolonged hospitalization,poor neurological outcomes,and high mortality in patients with aSAH.Previous studies considered cerebral vasospasm as the sole factor leading to DCI,while current research has confirmed that DCI is the result of the interaction between multiple mechanisms.This article summarizes the pathophysiological mechanisms leading to DCI after aSAH,in order to identify early warning indicators and treatment targets for DCI and improve the prognosis of patients.关键词
动脉瘤性蛛网膜下腔出血/迟发性脑缺血/病理生理学机制Key words
aneurysmal subarachnoid hemorrhage/delayed cerebral ischemia/pathophysiological mechanisms分类
医药卫生引用本文复制引用
李娜,张立平,孙晓曼,潘亚文..动脉瘤性蛛网膜下腔出血后迟发性脑缺血病理生理学机制的研究现状[J].国际神经病学神经外科学杂志,2025,52(4):53-60,8.基金项目
国家自然科学基金地区基金(82360566). （82360566）
