昆明医科大学学报2025，Vol.46Issue(8)：58-64,7.DOI:10.12259/j.issn.2095-610X.S20250808
BMD、T值、HU值和改良VBQ评分预测胸腰椎脆性骨折的效能分析
Efficacy Analysis of BMD,T-scores,HU Values,and Modified VBQ Scores in Predicting Thoracolumbar Fragility Fractures
摘要
Abstract
Objective To investigate the differences in BMD,T-scores,lumbar HU values,and modified VBQ scores in patients with thoracolumbar fractures,analyze their correlations,and evaluate their predictive efficacy for thoracolumbar fractures.Methods Patients with thoracolumbar fragility fractures and hospitalized in the Department of Orthopedics at the Second Affiliated Hospital of Kunming Medical University from January 2022 to March 2025 were retrospectively enrolled.Among them,132 eligible patients were divided into the fracture group(n=63)and the non-fracture group(n=69).BMD and T-scores of L1～L4 vertebrae were measured via DEXA,lumbar HU values were obtained from CT scans,and modified VBQ scores were calculated using lumbar MRI.Intergroup comparisons were performed using independent samples t-tests.Pearson's correlation analysis was used to assess the relationships among BMD,T-scores,HU values,and modified VBQ scores.Receiver operating characteristic(ROC)curve analysis was conducted to evaluate their predictive performance for thoracolumbar fractures.Results The fracture group exhibited significantly lower mean BMD,T-scores,and HU values in L1～L4 compared to the non-fracture group,while modified VBQ scores were significantly higher(P<0.001).Correlation analysis revealed a significant positive correlation between BMD,T-scores,and HU values in L1～L4,whereas all three parameters showed a significant negative correlation with modified VBQ scores(P<0.001).The AUC values for predicting thoracolumbar fractures were 0.826(T-score),0.836(BMD),0.759(HU value),and 0.875(modified VBQ score),with optimal cutoff thresholds of-1.65(T-score),0.836 g/cm2(BMD),68.4(HU value),and 3.01(modified VBQ score),respectively.Conclusion BMD,T-scores,HU values,and modified VBQ scores in L1～L4 vertebrae are significantly correlated and can serve as the predictive indicators for thoracolumbar fractures.Among them,the modified VBQ score demonstrates the best predictive performance,making it a valuable auxiliary tool for assessing the vertebral bone quality.关键词
脆性骨折/骨密度/HU值/椎体骨质量评分Key words
Fragility fracture/Bone density/Hounsfield unit/Vertebral body quality score分类
医药卫生引用本文复制引用
徐世鑫,严荣爽,潘呈,罗洋,费德锐,李全,张颖..BMD、T值、HU值和改良VBQ评分预测胸腰椎脆性骨折的效能分析[J].昆明医科大学学报,2025,46(8):58-64,7.基金项目
国家自然科学基金(82060414) （82060414）
"兴滇英才支持计划"医疗卫生人才项目(XDYC-MY-2022-0026) （XDYC-MY-2022-0026）
