临床肝胆病杂志2025，Vol.41Issue(8)：1497-1503,7.DOI:10.12449/JCH250804
肝癌局部治疗策略
Locoregional therapeutic strategies for hepatocellular carcinoma
向华 1龙林 2张永琎 2周菊梅 3赵杨 4李慕梓 4刘韧耕 2石世雄 2王蓉蓉2
作者信息
- 1. 湖南省肿瘤医院(中南大学湘雅医学院附属肿瘤医院) 介入血管外科,长沙 410006||湖南省人民医院(湖南师范大学附属第一医院)介入血管外科,长沙 410000
- 2. 湖南省人民医院(湖南师范大学附属第一医院)介入血管外科,长沙 410000
- 3. 湖南省肿瘤医院(中南大学湘雅医学院附属肿瘤医院) 腹部放疗科,长沙 410006
- 4. 湖南省肿瘤医院(中南大学湘雅医学院附属肿瘤医院) 介入血管外科,长沙 410006
- 折叠
摘要
Abstract
The incidence and mortality rates of hepatocellular carcinoma(HCC)remain high in China,and the application of surgical resection is often limited due to the fact that most patients are in the advanced stage at the time of confirmed diagnosis.This article reviews commonly used advanced locoregional therapies for HCC and the advances in mainstream techniques such as local ablation(radiofrequency ablation,microwave ablation,irreversible electroporation,and cryoablation),intravascular intervention(transcatheter arterial chemoembolization,hepatic arterial infusion chemotherapy,and Y90 hepatic arterial infusion chemotherapy),and radiotherapy(CyberKnife,proton therapy,and heavy-ion therapy),and a multidimensional decision-making framework is constructed for HCC locoregional therapy by comparing treatment principles,indications,limitations,and clinical data of these techniques.This article aims to provide evidence-based support for persistent dilemmas in clinical decision-making,promote the role of locoregional therapies in clinical practice,and propose the directions for future research and clinical application.This article also establishes a comprehensive clinical roadmap for HCC locoregional therapy,which helps to address current challenges regarding technique selection and delineate future directions for innovation,in order to reshape the treatment of HCC through technological integration and paradigm innovation.关键词
肝肿瘤/肿瘤治疗方案/精准医学Key words
Liver Neoplasms/Antineoplastic Protocols/Precision Medicine引用本文复制引用
向华,龙林,张永琎,周菊梅,赵杨,李慕梓,刘韧耕,石世雄,王蓉蓉..肝癌局部治疗策略[J].临床肝胆病杂志,2025,41(8):1497-1503,7.
