新医学2025，Vol.56Issue(9)：858-864,7.DOI:10.12464/j.issn.0253-9802.2025-0212
多焦点与单焦点硬性透气性角膜接触镜控制青少年高度近视进展的对比研究
A comparative study on the control of high myopia progression in adolescents using multifocal and single-vision rigid gas permeable contact lenses
摘要
Abstract
Objective To compare the efficacy and safety of multifocal rigid gas permeable(MFRGP)lenses versus single-vision rigid gas permeable(SVRGP)lenses in controlling myopia progression in adolescents aged 8 to 14 with high myopia.Methods A total of 120 adolescent patients with high myopia,who visited the Guangdong Provincial People's Hospital between 2021 and 2023,were enrolled.Based on their myopia correction method,the patients were divided into the MFRGP group(58 cases)and the SVRGP group(62 cases).Follow-up was conducted for 1 year,during which we assessed their spherical equivalent(SE),annual increase of axial length(AL),visual acuity with lenses,residual SE,and the incidence of corneal adverse reactions.Results Both groups showed an increasing trend in SE and AL.In the MFRGP group,the SE change was(-0.40±0.31)D and and the AL growth was(0.25±0.13)mm,while in the SVRGP group,the SE change was(-0.62±0.37)D and the AL growth was(0.38±0.27)mm.The differences in the SE and AL increment changes between and within the two groups were statistically significant(all P<0.05).At 12 months,the MFRGP group had better corrected visual acuity than the SVRGP group[LogMAR:+0.02±0.06 vs.+0.10±0.09,P<0.001],and the residual SE was significantly lower than that in the SVRGP group[(-0.29±0.31)D vs.(-0.78±0.71)D,P=0.002].No severe complications occurred in either group,and although the MFRGP group had a slightly higher probability of adverse reactions compared with the SVRGP group,the difference was not statistically significant and could be alleviated with intervention.Conclusions MFRGP is superior to SVRGP in controlling the progression of high myopia in adolescents,and its safety is controllable.MFRGP shows better clinical efficacy in myopia prevention and control.关键词
高度近视/多焦点硬性透气性角膜接触镜/单焦点硬性透气性角膜接触镜/等效球镜度/眼轴长度Key words
High myopia/Multifocal rigid gas permeable contact lens/Single vision rigid gas permeable contact lens/Spherical equivalent/Axial length引用本文复制引用
杨静,罗葭淇,谢文娟,杨诚,李雨蔓,黎峥,曾锦..多焦点与单焦点硬性透气性角膜接触镜控制青少年高度近视进展的对比研究[J].新医学,2025,56(9):858-864,7.基金项目
广东省自然科学基金面上项目(2021A1515011822) （2021A1515011822）
