无机材料学报2025，Vol.40Issue(8)：849-859,11.DOI:10.15541/jim20250001
无机生物材料调控神经细胞功能及神经化组织再生的研究进展
Inorganic Biomaterials on Regulating Neural Cell Function and Innervated Tissue Regeneration:A Review
摘要
Abstract
In regard to the crucial role of nerves in tissue regeneration,developing tissue engineering scaffolds with neural-activities has attracted more attention.Recently,inorganic biomaterials have been extensively used in regulating neural cell functions and innervated tissue regeneration due to their advantages of highly controllable chemical compositions,micro/nano topographical structures,and excellent physicochemical properties.This review firstly introduces the typical used inorganic biomaterials for neural regulation,including bioceramics and electroactive materials,and then elaborates on their biological effects of enhancing neural cell viabilities and functions through modulating cell behaviors,regulating immune microenvironment,and constructing electroactive microenvironment.Subsequently,recent progress of inorganic biomaterials on various innervated tissue regeneration,such as spinal cord,peripheral nerves,skin,skeletal muscles,and cavernous tissues,is summarized.Finally,the current challenges and future perspectives of inorganic biomaterials in innervated tissue regeneration are discussed.关键词
无机生物材料/生物陶瓷/电活性材料/组织再生/神经化/综述Key words
inorganic biomaterial/bioceramic/electroactive material/tissue regeneration/innervation/review分类
化学化工引用本文复制引用
张洪健,赵梓壹,吴成铁..无机生物材料调控神经细胞功能及神经化组织再生的研究进展[J].无机材料学报,2025,40(8):849-859,11.基金项目
中国科学院国际合作局所级中外联合研究单元(121631ZYLH20240014)Joint Research Unit Plan of Chinese Academy of Sciences(121631ZYLH20240014) （121631ZYLH20240014）
