无机材料学报2025，Vol.40Issue(8)：921-932,12.DOI:10.15541/jim20240541
微纳米生物活性玻璃:功能化设计与血管化皮肤再生
Micro-nanoscale Bioactive Glass:Functionalized Design and Angiogenic Skin Regeneration
摘要
Abstract
Bioactive glass(BG)is an important class of amorphous inorganic biomaterials,which has been clinically used in hard tissue repair for many years,exhibiting unique tissue repair activity.Recent studies have found that BG also shows effective repair activity in soft tissue,demonstrating significant application potential.Compared with traditional BG,micro-nanoscale bioactive glass(MNBG)has a unique micro-nano structure,which not only retains its excellent chemical composition but also has a larger specific surface area and higher reactivity.These special structures and properties enable MNBG to exhibit significant application potential in promoting vascularization and skin repair/regeneration.This work focuses on the research progress of MNBG in regulating vascularization and skin regeneration,including the abilities of MNBG to promote vascularization and regulate immune cell function,as well as its antioxidant,anti-inflammatory,and antibacterial properties.These characteristics enable MNBG to effectively stimulate blood vessel formation,reduce inflammation,and inhibit bacterial infection,thus promoting wound healing and tissue repair.This paper summarizes the key research on the role of MNBG in vascularization and skin wound repair and offers recommendations on the existing issues and future research directions in the application of MNBG in skin wound repair,aiming to promote the application transformation of MNBG in the field of skin repair.关键词
微纳米生物活性玻璃/血管化/皮肤再生/生物活性材料/综述Key words
micro-nanoscale bioactive glass/vascularization/skin regeneration/bioactive material/review分类
化学化工引用本文复制引用
艾敏慧,雷波..微纳米生物活性玻璃:功能化设计与血管化皮肤再生[J].无机材料学报,2025,40(8):921-932,12.基金项目
国家自然科学基金(52172288,52302354,52411540232)National Natural Science Foundation of China(52172288,52302354,52411540232) （52172288,52302354,52411540232）
