中国兽医杂志2025,Vol.61Issue(9):119-126,8.DOI:10.20157/j.cnki.zgsyzz.2025.09.014
非洲猪瘟病毒感染诱导猪体内细胞因子表达变化的研究进展
Advances in Cytokine Expression Changes Induced by African Swine Fever Virus Infection in Pigs
摘要
Abstract
African swine fever(ASF)is an acute,highly fatal infectious disease caused by African swine fever virus(ASFV),which has inflicted substantial economic losses on the global pig industry.Due to the lack of safe and effective vaccines or treatments currently available on the market,in-depth investigation into the pathogenesis and host immune responses of ASF is crucial for its control and prevention.Cytokines,as key mediators of immune regulation,undergo dynamic changes that not only reflect the immune status of the host but also provide vital clues for understanding the interaction mechanisms between the virus and the host immune system.This review summarizes recent research progress on cytokine expression patterns following ASFV infection in pigs and systematically analyzes the relationship between ASFV infection and cytokine alterations.The aim is to offer new insights and theoretical foundations for further exploration of the immune response mechanisms in pigs infected with ASFV.关键词
非洲猪瘟(ASF)/非洲猪瘟病毒(ASFV)/细胞因子/白细胞介素/干扰素Key words
African swine fever(ASF)/African swine fever virus(ASFV)/cytokine/interleukin/interferon分类
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殷磊,李志娟,左媛媛,戈胜强,李桂梅,初薛霏,李金明,王志亮..非洲猪瘟病毒感染诱导猪体内细胞因子表达变化的研究进展[J].中国兽医杂志,2025,61(9):119-126,8.基金项目
国家重点研发计划项目(2022YFD1800500) (2022YFD1800500)