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m6A甲基化修饰参与畜禽氧化应激调控的研究进展

姚佳岐 李鑫 王天润 邓茹雪 胡晓东 孙涵钰 王雪

中国畜牧杂志2025,Vol.61Issue(9):21-28,8.
中国畜牧杂志2025,Vol.61Issue(9):21-28,8.DOI:10.19556/j.0258-7033.20240701-06

m6A甲基化修饰参与畜禽氧化应激调控的研究进展

Research Progress on the Involvement of m6A Methylation Modification in the Regulation of Oxidative Stress in Livestock

姚佳岐 1李鑫 1王天润 1邓茹雪 1胡晓东 1孙涵钰 1王雪1

作者信息

  • 1. 黑龙江八一农垦大学动物科技学院,黑龙江省寒区白鹅种质资源发掘与创新利用重点实验室,黑龙江 大庆 163319
  • 折叠

摘要

Abstract

Oxidative stress will cause cells to produce excessive reactive oxygen species radicals,damage mitochondria and endoplasmic reticulum,reduce the immune function of animals,and cause diseases and cause serious losses to animal husbandry.In epigenetics,m6A methylation,as one of the important RNA modification methods,has become a hot spot in genetics and molecular biology research.m6A methylation can regulate oxidative stress-related genes through related methyltransferases and demethyltransferases,and then participate in the whole process of oxidative stress.In this review,we will elaborate on the taxonomic function of m6A methylation-related enzymes and the role of m6A methylation modification in the regulatory mechanism of oxidative stress in livestock,aiming to promote the further development of m6A methylation in the field of oxidative stress in livestock.

关键词

m6A甲基化/氧化应激/畜禽

Key words

m6A methylation/Oxidative stress/Livestock

分类

农业科技

引用本文复制引用

姚佳岐,李鑫,王天润,邓茹雪,胡晓东,孙涵钰,王雪..m6A甲基化修饰参与畜禽氧化应激调控的研究进展[J].中国畜牧杂志,2025,61(9):21-28,8.

基金项目

国自然青年科学基金项目C类(32102543) (32102543)

黑龙江八一农垦大学学成、人才启动计划项目(XYB202016) (XYB202016)

黑龙江省双一流特色学科平台项目(HLJTSXK2022) (HLJTSXK2022)

黑龙江八一农垦大学"三横三纵"计划项目(ZRCQC202306) (ZRCQC202306)

黑龙江省博士后科学基金项目(LBH-Z22233) (LBH-Z22233)

中国畜牧杂志

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