摘要
Abstract
Objective To observe the changes of vitamin D levels in patients with Benign Paroxysmal Positional Vertigo(BPPV)after rehabilitation,and to explore the correlation between the risk of recurrence and vitamin D levels after anterior hall functional recovery in patients with otolithiasis.Methods Rehabilitation treatments were provided to 283 patients diagnosed with otolithiasis in our hospital.The patients were grouped according to the serum vitamin D content before recovery and the recurrence after recovery,and the general clinical data,biochemical indexes and scores of the patients in different groups were collected.BBS to score vertigo,vestibular symptom index,and balance in patients with otolithiasis.Stratified regression analysis was performed to analyze the relationship between different scoring systems and vitamin D levels in patients with otolithiasis.Multivariate logistic regression analysis,restrictive cubic spline model and survival curve were used to analyze the association between vitamin D level and the risk of BPPV recurrence.The E-value method was used to analyze the sensitivity of the factors affecting the recurrence of vestibular function after rehabilitation in patients with otolithiasis.Results There were statistically significant scores in the vitamin D deficiency group,vitamin D deficiency group,and vitamin D adequacy group in VSI score,VSS-SF score and BBS score(P<0.05).VSI score,VSS-SF score and BBS score were negatively correlated with vitamin D level,and with the decrease of vitamin level,VSI score,VSS-SF score and BBS score increased.There were statistically significant levels of serum vitamin D content,hypertension,diabetes mellitus,hyperlipidemia,VSI score,VSS-SF score and BBS score in the recurrence group and the non-recurrence group(P<0.05).With the increase of vitamin D deficiency,the recurrence rate of patients increased,and the recurrence rate of vitamin D deficiency group was significantly higher than that of vitamin D deficiency and vitamin D adequacy group,and hypertension,diabetes mellitus,and hyperlipidemia could also increase the risk of recurrence.Conclusions This study has found that the decrease of vitamin D level in patients with BPPV can affect the indicators of vestibular function and increase the risk of recurrence,and hypertension,diabetes mellitus,and hyperlipidemia are also risk factors for recurrence after recovery.关键词
耳石症/前庭功能/复发/维生素DKey words
Otolithiasis/Vestibular function/Relapse/Vitamin D分类
医药卫生
