中国医学科学院学报2025，Vol.47Issue(4)：535-541,7.DOI:10.3881/j.issn.1000-503X.16373
六分钟步行试验对急性高山病的预测价值
Value of 6-Minute Walking Test in Predicting Acute Mountain Sickness
摘要
Abstract
Objective To evaluate the value of pre-ascent 6-minute walking test performed at a high altitude in predicting the incidence of acute mountain sickness(AMS)induced by rapid ascent to a very high altitude.Methods After baseline information was collected,participants completed the 6-minute walking test at a high altitude of 2 900 m.Then,they rapidly ascended to a very high altitude of 5 000 m.The Lake Louise score was recorded to assess AMS.Results The AMS group showed a shorter pre-ascent 6-minute walking distance(6MWD)at the high altitude than the non-AMS group[480.00(450.00,521.75)m vs.546.00(516.50,568.50)m,P=0.006].No difference was observed regarding the pre-ascent heart rate or peripheral oxygen saturation(both P＞0.05).The pre-ascent 6MWD at the high altitude was negatively correlated with the Lake Louise score assessed after rapid ascent to the very high altitude(r=-0.497,P=0.012).Logistic regression analysis confirmed that the pre-ascent 6MWD at the high altitude was associated with the risk of AMS induced by rapid ascent to the very high altitude(OR=0.971,95％CI=0.947-0.996,P=0.022).The results indi-cated that the pre-ascent 6MWD demonstrated ideal prediction performance(area under receiver operating char-acteristic curve=0.846,P=0.006).Conclusion The pre-ascent 6MWD recorded at the high altitude is a convenient and reliable predictor of the AMS induced by rapid ascent to the very high altitude.关键词
急性高山病/6 min步行试验/Lake Louise评分Key words
acute mountain sickness/6-minute walking test/Lake Louise score分类
医药卫生引用本文复制引用
江雨凡,马强,陈海威,韩宝石,冯斌,陈韵岱..六分钟步行试验对急性高山病的预测价值[J].中国医学科学院学报,2025,47(4):535-541,7.基金项目
国家重点研发计划(2020YFC1512305)和军队卫生防疫防护专项(Z2FYFH12) （2020YFC1512305）
