中国普通外科杂志2025，Vol.34Issue(7)：1331-1339,9.DOI:10.7659/j.issn.1005-6947.250368
肝癌合并血管侵犯的治疗策略及研究进展
Therapeutic strategies and research progress in hepatocellular carcinoma with vascular invasion
摘要
Abstract
Hepatocellular carcinoma(HCC)is characterized by a high propensity for vascular invasion,frequently leading to the formation of tumor thrombi,which significantly affect prognosis and therapeutic decision-making.Microvascular invasion(MVI)is a key predictor of postoperative recurrence,whereas the presence of macrovascular tumor thrombus indicates advanced disease.In recent years,notable progress has been made in the standardized diagnosis,preoperative prediction,and individualized treatment strategies for vascular tumor thrombi.The integration of radiomics and biomarkers has markedly improved the accuracy of preoperative MVI prediction,while various neoadjuvant and adjuvant treatment approaches have shown potential in controlling postoperative recurrence.Despite continuous optimization of diagnostic and therapeutic systems,challenges remain,including tumor heterogeneity,the lack of dynamic monitoring tools,and the difficulty in improving survival rates in high-risk patients.This review summarizes recent advances in the field of vascular tumor thrombi in HCC,aiming to provide theoretical support for clinical practice and to promote the development of individualized precision therapy.关键词
癌,肝细胞/肿瘤浸润/门静脉/肝静脉/精准医学Key words
Hepatocellular Carcinoma/Neoplasm Invasiveness/Portal Vein/Hepatic Veins/Precision Medicine分类
医药卫生引用本文复制引用
陈荣晨,柳宗翰,程树群..肝癌合并血管侵犯的治疗策略及研究进展[J].中国普通外科杂志,2025,34(7):1331-1339,9.基金项目
中国国家重点研究开发基金资助项目(2022YFC2503700) （2022YFC2503700）
上海市重中之重临床医学中心建设基金资助项目(2023ZZ02005). （2023ZZ02005）
