中国当代儿科杂志2025，Vol.27Issue(9)：1057-1061,5.DOI:10.7499/j.issn.1008-8830.2503110
远程黄疸监测系统在新生儿高胆红素血症居家筛查中的临床转化可行性研究
Feasibility study on the clinical translation of a remote jaundice monitoring system for home-based screening of neonatal hyperbilirubinemia
摘要
Abstract
Objective To evaluate the clinical utility and translational potential of a remote jaundice monitoring system for home-based screening of neonatal hyperbilirubinemia.Methods A prospective self-controlled study was conducted,enrolling 538 newborns with gestational age≥35 weeks,birth weight≥2 000 g,and postnatal age≤14 days at the Women's Hospital of Nanjing Medical University from March to October 2023.Four screening protocols with different predictive indicators were developed based on the Chinese Neonatal Transcutaneous Hourly Bilirubin Nomogram.The effectiveness of the system was evaluated,and the feasibility of using the remote jaundice monitoring system in actual home settings was analyzed.Results A total of 538 paired transcutaneous bilirubin(TcB)and total serum bilirubin(TSB)measurements showed a strong correlation(r=0.85,P＜0.001),with 95.0%(511/538)of samples within the 95%limits of agreement.Using TcB≥the 95th percentile as the predictive indicator,the system achieved 100%sensitivity,46.2%specificity,and an area under the receiver operating characteristic curve of 0.731(95%CI:0.682-0.780).This approach could reduce unnecessary hospital visits by 41.4%(221/538).Conclusions The system integrates the QBH-801 transcutaneous bilirubinometer,intelligent early warning,and remote guidance services,establishing a closed-loop"hospital-to-home"management model.It demonstrates high safety and feasibility,with significant clinical translational value.关键词
新生儿高胆红素血症/经皮胆红素/居家筛查/新生儿Key words
Neonatal hyperbilirubinemia/Transcutaneous bilirubin/Home screening/Newborn引用本文复制引用
孙小凡,郑意,苏爱玲,韩树萍,董小玥..远程黄疸监测系统在新生儿高胆红素血症居家筛查中的临床转化可行性研究[J].中国当代儿科杂志,2025,27(9):1057-1061,5.基金项目
江苏省医学会医学科研专项资金项目(SYH-32034-0072) （SYH-32034-0072）
南京医科大学科技发展基金(NMUB20220113). （NMUB20220113）
