中国畜禽种业2025，Vol.21Issue(8)：33-41,9.
液相芯片技术在动物遗传育种中的应用与发展
Application and Development of Liquid Chip Technology in Animal Genetics and Breeding
摘要
Abstract
Liquid phase chip is a technology used for high-throughput genotyping.Compared with genome resequencing and sol-id-phase chips,it has the advantages of more flexible detection site selection,lower chip development and detection costs.This technology is based on two different technical systems,multiplex PCR and probe hybridization capture,and can meet the genotype typing needs of low,medium,and high SNP densities.It has been widely used in the identification of germplasm resources,impor-tant trait mining,and variety breeding and improvement of domestic animals(cattle,sheep,pigs,chickens,silkworms,etc.).This ar-ticle reviews and analyzes the principles of liquid-phase chip technology,its research progress in domestic animals,and the prob-lems and challenges it faces in practical applications.The aim is to provide effective technical support for the industrial application of this technology and genetic breeding research in domestic animals.关键词
液相芯片/高通量基因分型/动物遗传育种Key words
Liquid phase chip/High-throughput genotyping/Animal genetics and breeding分类
农业科技引用本文复制引用
丁文家,魏大为,杨尚,陈宁博,马云,雷初朝,黄永震..液相芯片技术在动物遗传育种中的应用与发展[J].中国畜禽种业,2025,21(8):33-41,9.基金项目
科技创新2030—重大项目(2023ZD040480206) （2023ZD040480206）
宁夏回族自治区重点研发计划(2024BBF01007) （2024BBF01007）
河南省农业科学院自主创新项目(2024ZC128) （2024ZC128）
国家现代农业产业技术体系(CARS-37). （CARS-37）
