表面技术2025，Vol.54Issue(18)：16-26,11.DOI:10.16490/j.cnki.issn.1001-3660.2025.18.002
功能涂层在生物医用纤维材料中的研究进展
A Review of Functional Coatings in Biomedical Fiber Materials
摘要
Abstract
As an advanced surface modification technology,functional coatings provide strong support for the application of fiber materials in biomedical fields such as antibacterial and protection,monitoring and diagnosis,therapy and rehabilitation.The work aims to systematically review the latest research progress of functional coatings in biomedical fiber materials,conducting in-depth analysis from three aspects of technical principles,functional structures,and multi-scenario applications.In the field of biomedical application,the research of functional coatings focuses on improving the biocompatibility of fiber materials in contact with biological tissues,and strengthening the specific biomedical properties of fiber materials such as repairing biological tissues.The functional coatings of biomedical fiber materials are discussed from four application parts,which mainly contains antibacterial and protection,monitoring and diagnosis,therapy and rehabilitation,and multi-functional integration. For the antibacterial and protection application,antibacterial compounds such as metal nanoparticles can be coated on the fiber materials to prepare the functional coating,which can improve the microbial inactivation efficiency of medical fiber materials.The functional coating for the monitoring and diagnosis realizes the functions of physiological signal monitoring and biosensing detection by forming fiber materials with conductive and sensing structures.The micro-nano coating with the conductive material can be used to prepare smart fiber materials,facilitating the acquisition and analysis of human physiological signals.In the field of therapy and rehabilitation,fiber materials with functional coatings can play a key role in tissue repair,hemostasis and coagulation by loading bioactive molecules such as drugs and growth factors onto coatings.Moreover,the coatings on fiber materials are also required for the application in artificial organs,because the coatings can improve the biocompatibility of the fiber materials.In addition,fiber materials with multiple functions are more suitable for practical medical applications.For example,the multi-modal fabrics with antibacterial protection and real-time motion monitoring can be developed by multi-dimensional material design and interface engineering. Although the existing research of the functional coating on fiber materials has made significant progress,there are still some challenges.At present,the types of the coating materials are limited,and the preparation of functional coatings still needs to be controlled accurately.More importantly,the function coatings of the fiber materials for clinical medical applications are required to match well.With the continuous advancement of scientific research and engineering technology,functional coatings in biomedical fiber materials will also be continuously developed.By using natural biodegradable polymers and optimizing the coating process,the functional coatings can be used to construct a bionic structure with improved environmental adaptability.For instance,the biocompatibility and long-term stability of the coatings can be enhanced by biomimetic design and interface engineering.In view of the implant fiber material,the coating in the inner layer of the fiber can promote cell adhesion with anti-immune activity,and the superhydrophobic coatings for anti-adhesion are prepared in the outer layer.In order to further improve the biomedical application of fiber materials,future research should focus on developing intelligent coating materials and multi-functional integration,and continuously improve the biological and environmental adaptability of fiber materials to promote the coordinated development of functional coatings and fiber materials.关键词
功能涂层/纤维材料/生物医用/柔性穿戴/仿生设计Key words
functional coating/fiber materials/biomedical application/smart wearable/bionic design分类
通用工业技术引用本文复制引用
邢家益,赖恩平,贾伟,高明,刘向..功能涂层在生物医用纤维材料中的研究进展[J].表面技术,2025,54(18):16-26,11.基金项目
新疆维吾尔自治区高校基本科研业务费科研项目(XJEDU2023P030) （XJEDU2023P030）
新疆维吾尔自治区天池英才青年博士项目(5105240151n) （5105240151n）
深圳市科技重大专项(KJZD20230923113303006) （KJZD20230923113303006）
新疆大学博士科研启动基金项目(620323013)the Scientific Research Program of the Higher Education Institution of Xinjiang,China(XJEDU2023P030) （620323013）
The Tianchi Talent Program of Xinjiang Uygur Autonomous Region in China(5105240151n) （5105240151n）
the Shenzhen Science and Technology Program(KJZD20230923113303006)and the PhD research startup foundation of Xinjiang University(620323013) （KJZD20230923113303006）
