滨州医学院学报2025，Vol.48Issue(4)：361-365,5.DOI:10.19739/j.cnki.issn1001-9510.2025.04.005
体外血流控制装置防治颈动脉内膜剥脱术后脑过度灌注综合征的临床疗效
The clinical value of extracorporeal blood flow control in the prevention and treatment of hyperperfusion syndrome after carotid endarterectomy
王奇星 1郭翀 1李承龙 1黄蕴 1张文生1
作者信息
- 1. 滨州医学院附属医院神经外科 山东滨州 256603
- 折叠
摘要
Abstract
Objective To investigate the clinical value of in vitro blood flow control in the prevention and treatment of cere-bral hyperperfusion syndrome(CHS)after carotid endarterectomy(CEA).Methods A retrospective analysis was conducted on 41 patients with carotid endarterectomy who exhibited a rise in brain oxygen saturation of more than 10％.These patients were di-vided into an observation group and a control group based on whether an external blood flow control device was used during the procedure.The clinical efficacy of the two groups was compared,and the neurological function[Mini-Mental State Examination(MMSE),National Institutes of Health Stroke Scale(NIHSS)]of the two groups before and after surgery was analyzed.The inci-dence of complications in both groups within 30 days after surgery was recorded and statistically analyzed.Results The MMSE score of observation group was(28.90±1.70),which was higher than that of control group(25.81±6.54).The NIHSS score of(12.30±1.10)was lower than that of the control group(16.24±6.73),with statistical significance(P＜0.05 or P＜0.01);the incidence of complications in the observation group was 5.00％,which was lower than that in the control group(38.10％),with a statistically significant difference(P＜0.05);There was no significant difference in the incidence of complications such as myocardial infarction,cerebral infarction,wound hematoma,incision infection,and nerve damage between the two groups.Conclu-sion The use of extracorporeal blood flow control devices during CEA can significantly reduce the incidence of cerebral hyperperfu-sion syndrome(CHS)postoperatively,providing a new research direction for the clinical prevention and treatment of CHS.关键词
体外血流控制装置/颈动脉内膜剥脱术/脑过度灌注Key words
extracorporeal blood flow control device/carotid endarterectomy/cerebral hyperperfusion分类
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王奇星,郭翀,李承龙,黄蕴,张文生..体外血流控制装置防治颈动脉内膜剥脱术后脑过度灌注综合征的临床疗效[J].滨州医学院学报,2025,48(4):361-365,5.
