成都大学学报（自然科学版）2025，Vol.44Issue(3)：232-238,7.DOI:10.3969/j.issn.1004-5422.2025.03.002
细胞外囊泡的分离纯化及作为药物载体的研究进展
Research Progress on Isolation,Purification of Extracellular Vesicles,and Their Function as Drug Carriers
摘要
Abstract
Extracellular vesicles(EVs)are secreted by eukaryotes and prokaryotes and are responsible for transferring DNA,RNA,protein,lipid,and metabolites from donating cells to receptor cells.EVs can en-capsulate drugs,such as nucleic acid,protein,polysaccharide,and small molecules via physical,chemical or biological engineering methods.Due to their good biocompatibility and high stability,EVs are ideal nano carriers for active molecules,able to induce signal transduction,modulate immune systems,or con-duct other treatments.Particularly,they can target to special cells.In this review,the formation,classifica-tion,compositions,isolation,purification of EVs,and their function as drug carriers are summarized.This study will provide valuable reference for the application of EVs in formulation field.关键词
EVs/分离/药物载体/药物递送Key words
extracellular vesicles/isolation/drug carriers/drug delivery分类
医药卫生引用本文复制引用
段东延,蒋佳沂,周淑雅,李馨烨,姚倩..细胞外囊泡的分离纯化及作为药物载体的研究进展[J].成都大学学报（自然科学版）,2025,44(3):232-238,7.基金项目
成都大学2024年大学生创新训练项目(202411079015) （202411079015）
