发光学报2025，Vol.46Issue(9)：1649-1663,15.DOI:10.37188/CJL.20250062
NaErF4基近红外二区纳米发光材料的生物应用进展
Recent Advances in Biological Applications of NaErF4-based NIR-Ⅱ Luminescent Nanomaterials
摘要
Abstract
Compared to the visible and near-infrared-Ⅰ(NIR-Ⅰ)spectral regions,the near-infrared-Ⅱ(NIR-Ⅱ,1 000-1 700 nm)window has emerged as a promising frontier in bioimaging due to its greater tissue penetration depth and reduced spontaneous background fluorescence.In recent years,significant progress has been made in ap-plying Er3+-rich systems(NaErF4)as NIR-Ⅱ fluorescent probes in biomedical photonics.These studies not only fo-cus on enhancing imaging signal-to-noise ratios and detection sensitivity but also aim to achieve precision imaging-guided therapy for tumor regions.This review systematically summarizes the design strategies,luminescence mecha-nisms,and recent advances in the biological applications of NaErF4-based NIR-Ⅱ luminescent nanomaterials.Addi-tionally,the challenges associated with their future translation are discussed.关键词
NaErF4/近红外二区/下转移发射/荧光成像/成像引导治疗Key words
NaErF4/NIR-Ⅱ/downshifting emission/fluorescent imaging/imaging-guided therapy分类
数理科学引用本文复制引用
邓皓中,王旺,陈浩然,常钰磊..NaErF4基近红外二区纳米发光材料的生物应用进展[J].发光学报,2025,46(9):1649-1663,15.基金项目
国家自然科学基金(62075217,62475262,62305329,12404496) （62075217,62475262,62305329,12404496）
吉林省科技厅项目(20230508104RC,20230402039GH,20220201247JC) （20230508104RC,20230402039GH,20220201247JC）
长春市科技局(23GZZ06) （23GZZ06）
中国博士后科学基金(2023M733432,2023M741350)Supported by National Natural Science Foundation of China(62075217,62475262,62305329,12404496) （2023M733432,2023M741350）
Project of Science and Technology Agency,Jilin Province(20230508104RC,20230402039GH,20220201247JC) （20230508104RC,20230402039GH,20220201247JC）
Changchun Science and Tech-nology Bureau(23GZZ06) （23GZZ06）
China Postdoctoral Science Foundation(2023M733432,2023M741350) （2023M733432,2023M741350）
