神经损伤与功能重建2025，Vol.20Issue(9)：529-532,546,5.DOI:10.16780/j.cnki.sjssgncj.20240015
铜死亡参与阿尔茨海默病发病机制的研究进展
Research Progress on the Involvement of Cuproptosis in the Pathogenesis of Alzheimer's Disease
摘要
Abstract
Cuproptosis is a newly discovered form of cell death in recent years,while Alzheimer's Disease(AD)is a progressively developing neurodegenerative disorder of the central nervous system with insidious onset.Copper is involved in multiple pathogenic mechanisms of AD,and copper imbalance can induce the death of neurons and glial cells through these distinct mechanisms,thereby contributing to the onset of AD.This review summarizes recent research on the involvement of cuproptosis in the pathogenesis of AD.关键词
阿尔茨海默病/铜死亡/氧化应激/Aβ/tau蛋白/胶质细胞Key words
Alzheimer's disease/Cuprotosis/oxidative stress/Aβ/tau protein/glial cells分类
医药卫生引用本文复制引用
刘晓东,黄琴,徐平..铜死亡参与阿尔茨海默病发病机制的研究进展[J].神经损伤与功能重建,2025,20(9):529-532,546,5.基金项目
国家自然科学基金(ATAD3A调控线粒体动力学在OSAS大鼠认知障碍中的机制研究,No.82060218) （ATAD3A调控线粒体动力学在OSAS大鼠认知障碍中的机制研究,No.82060218）
