湖南中医药大学学报2025，Vol.45Issue(9)：1607-1612,6.DOI:10.3969/j.issn.1674-070X.2025.09.003
输卵管性不孕辅助生殖中西医结合全程干预的临床策略
Clinical strategy for whole-course intervention with integrated Chinese and Western medicine in assisted reproductive technology for tubal infertility
摘要
Abstract
Tubal infertility is a common and frequently occurring disease that significantly impacts female reproductive health and safety.Based on the reproductive theory of"uterus-centered five zang organs integration view"in Chinese medicine(CM),this paper systematically explores a whole-course intervention with integrated Chinese and Western medicine in assisted reproductive technology for tubal infertility.Professor YOU Zhaoling proposes that the core pathogenesis is the impairment of the collaterals and obstruction of the meridians in the uterus(fallopian tubes),and has established the comprehensive"four-stage and four-phase"treatment system that integrates and refines the four-stage diagnosis-treatment-management protocol(Protocols A,B,C,and D).Protocol A(CM Preconception Regulation and Treatment Protocol):Guided by the therapeutic principles of"regulating qi to dredge collaterals,resolving stagnation to unblock meridians,"it adopts a modified YOU's Fuyan Formula.Protocol B(Fertility Assistance Protocol):An appropriate oocyte retrieval protocol is selected based on the specific condition of the disease,and the embryo transfer timing is determined using three-dimensional transvaginal ultrasonography.Protocol C(Surgical Protocol):The treatment principle is to integrate elimination and tonification,combining internal and external therapeutic approaches to shorten the treatment course.Protocol D(CM Protocol for Antenatal Care After Conception):It focuses on dredging collaterals and nurturing the fetus as the basic therapeutic method with a modified YOU's Fetal Nourishing Formula.By analyzing the CM pathogenesis of tubal infertility,a phased and closed-loop diagnosis and treatment approach integrating Chinese and Western medicine is adopted to guide clinical prescription and medication.Through integrated internal and external treatment and phased management,the fallopian tube microenvironment is improved,and the pregnancy success rate is enhanced.关键词
输卵管性不孕/"四段四期"论治体系/辅助生殖技术/全过程管理/尤昭玲Key words
tubal infertility/"four-stage and four-phase"treatment system/assisted reproductive technology/whole-course management/YOU Zhaoling分类
医药卫生引用本文复制引用
张紫娟,杨瑞恩,游卉,尤昭玲..输卵管性不孕辅助生殖中西医结合全程干预的临床策略[J].湖南中医药大学学报,2025,45(9):1607-1612,6.基金项目
国家中医药管理局全国名中医传承工作室建设项目(国中医药办人教函[2022]5号) （国中医药办人教函[2022]5号）
湖南省自然科学基金项目(2025JJ80972) （2025JJ80972）
湖南创新型省份建设专项重点研发计划(2023SK2050) （2023SK2050）
湖南省创新型省份建设专项重点研发项目(2025JK2111). （2025JK2111）
