基础医学与临床2025，Vol.45Issue(10)：1270-1276,7.DOI:10.16352/j.issn.1001-6325.2025.10.1270
抗体药物偶联物在老年肿瘤患者中的治疗
Treatment of antibody-drug conjugates in elderly patients
摘要
Abstract
Antibody-drug conjugates(ADCs)are emerging anti-cancer drugs that have been widely applied in the treatment of hematological and solid tumors.ADCs deliver cytotoxic drugs to tumor cells with precision through anti-body targeting,enhancing efficacy while reducing side effects.Elderly cancer patients face treatment challenges due to factors such as drug metabolism,multiple comorbidities and decreased physical function.However,ADCs have therapeutic advantages in elderly patients.The article discusses the efficacy,safety,dosing strategies,and adverse reaction management of ADCs in elderly patients,in order to provide effective and safe treatment options for elderly cancer patients.关键词
抗体药物偶联物/老年患者/肿瘤治疗/靶向治疗Key words
antibody-drug conjugates/elder patients/cancer treatment/targeted therapy分类
医药卫生引用本文复制引用
刘丰硕,管梅..抗体药物偶联物在老年肿瘤患者中的治疗[J].基础医学与临床,2025,45(10):1270-1276,7.基金项目
中央高水平医院临床科研专项专科提升项目(2022-PUMCH-B-049) （2022-PUMCH-B-049）
