有色金属材料与工程2025，Vol.46Issue(4)：49-54,6.DOI:10.13258/j.cnki.nmme.20240313002
用于试纸条检测心梗标志物的PS微球制备及性能研究
Preparation and properties of polystyrene microspheres used for detecting myocardial infarction markers by transverse chromatography flow
摘要
Abstract
Polystyrene(polystyrene microsphere,PS)microspheres possess small particle size,large specific surface area,excellent dispersion,and facile modification.They are commonly employed in medical diagnostics and hold potential as detection materials in transverse chromatographic flow analysis.This study aims to prepare PS microspheres meeting the requirements for transverse chromatographic flow analysis by adjusting factors such as temperature and emulsifier and monomer dosage,and the PS microspheres was carboxylated and fluorescent labeling through seed modification and swelling,ultimately applied in the development of a transverse chromatographic flow detection strip.The successful preparation of PS microspheres with a particle size of approximately 50 nm was achieved,and the feasibility of fluorescence-based carboxylated PS microspheres for quantitatively detecting marker concentrations on test strips were successfully demonstrated.关键词
聚苯乙烯/乳液聚合/种子修饰/横向流动免疫层析技术Key words
polystyrene/emulsion polymerization/seed modification/lateral flow immunochromatography分类
通用工业技术引用本文复制引用
关盛文,徐京城..用于试纸条检测心梗标志物的PS微球制备及性能研究[J].有色金属材料与工程,2025,46(4):49-54,6.基金项目
苏州晶莹信息科技有限公司横向项目(H-2022-369-023) （H-2022-369-023）
