饲料研究2025,Vol.48Issue(15):19-24,6.DOI:10.13557/j.cnki.issn1002-2813.2025.15.004
解淀粉芽孢杆菌GB-9菌制剂对波尔山羊生长性能和健康情况的影响
Effects of Bacillus amyloliquefaciens GB-9 agent on growth performance and health statu of Boer goats
摘要
Abstract
The experiment aimed to investigate the effects of supplementing drinking water with Bacillus amyloliquefaciens GB-9 agent on the growth performance and health status of Boer goats.Active components of the GB-9 agent were identified through PCR amplification and mass spectrometry analysis,and its antimicrobial activity was evaluated via in vitro antibacterial assays.A feeding trial was conducted using Boer goats to screen effective doses of the GB-9 agent.The efficacy of the GB-9 agent in treating acute diarrhea in lambs,as well as its effects on herd immunity and growth performance were evaluated.The results showed that the GB-9 agent contains lipopeptide antimicrobial substances including surfactins,iturins and fengycins,and β-1,3-1,4-glucanase.It exhibited significant inhibitory effects against pathogenic microorganisms such as Staphylococcus aureus and Aspergillus niger,along with potential for modulating gut microbiota.Dose screening identified 0.004%as the effective supplementation concentration.Adding 0.01%GB-9 agent in drinking water cured acute lamb diarrhea and improved gut microbiota abundance,with effects superior to oxy tetracycline.Compared with the control group,the incidences of fever,diarrhea,loss of appetite,urinary tract infection,cold and runny nose,as well as the total incidence rate in the GB-9 bacterial preparation group of Boer goats were significantly decreased(P<0.05),the final weight and average daily weight gain were significantly increased(P<0.05).The study indicates that supplementing drinking water with 0.004%Bacillus amyloliquefaciens GB-9 agent enhances growth performance and reduces disease incidence in Boer goats.关键词
解淀粉芽孢杆菌GB-9菌制剂/脂肽/波尔山羊/生长性能/健康状况Key words
Bacillus amyloliquefaciens GB-9 agent/lipopeptides/Boer goats/growth performance/health status分类
农业科技引用本文复制引用
戴彬彬,钟波,谢婕妤,吕正兵..解淀粉芽孢杆菌GB-9菌制剂对波尔山羊生长性能和健康情况的影响[J].饲料研究,2025,48(15):19-24,6.基金项目
浙江省自然科学基金(项目编号:19042044-D) (项目编号:19042044-D)
横向合作项目(项目编号:24040742-J) (项目编号:24040742-J)