生殖医学杂志2025，Vol.34Issue(9)：1170-1175,6.DOI:10.3969/j.issn.1004-3845.2025.09.003
腹腔穿刺置管引流术治疗中重度OHSS患者的妊娠结局分析
Analysis of pregnancy outcomes after transabdominal paracentesis and indwelling catheter drainage in treatment of patients with moderate and severe ovarian hyperstimulation syndrome
摘要
Abstract
Objective:To evaluate the effect of abdominal paracentesis and catheter drainage on pregnancy outcomes in patients with moderate to severe ovarian hyperstimulation syndrome(OHSS)accompanied by ascites. Methods:A retrospective analysis was conducted on the clinical data of 437 patients with moderate to severe OHSS and ascites who underwent embryo transfer and were admitted to the reproductive gynecology department of Northwest Women's and Children's Hospital from April 2019 to August 2023.The patients were divided into a catheter group(125 cases,who underwent abdominal paracentesis and catheter drainage)and a control group(312 cases,who did not receive the treatment mentioned above).The basic information,ovulation induction status,and pregnancy outcomes were compared between the two groups.Logistic regression analysis was used to evaluate the effect of abdominal indwelling catheters on live birth rates. Results:There were no significant differences in age,polycystic ovary syndrome(PCOS)prevalence,duration of infertility,gonadotropin(Gn)usage,and type of transplanted embryo between the two groups(P＞0.05).The serum estradiol(E2)level and number of retrieved oocytes on the trigger day were significantly higher in the catheter group than those in the control group(P＜0.05).The duration of catheter indwelling in the catheter group ranged from 1 to 24 days,with an average of(7.80±3.86)days.No complications related to catheter placement,such as infection or intra-abdominal organ injury,were observed.There were no significant differences in clinical pregnancy rate,miscarriage rate,premature birth rate,live birth rate,birth weight of newborns from singleton and twin deliveries,gestational age at delivery,and incidence of hypertensive disorders of pregnancy and gestational diabetes between the catheter group and the control group(P＞0.05).Logistic regression analysis showed that abdominal indweuing catheters had no statistically significant effect on the live birth rate[OR=1.352,95％CI(0.735,2.485),P=0.332]. Conclusions:Abdominal paracentesis combined with catheter drainage is effective treatment for moderate to severe OHSS accompanied by ascites and has no significant adverse effects on pregnancy outcomes in such patients.关键词
卵巢过度刺激综合征/腹水/腹腔穿刺/置管引流/体外受精-胚胎移植Key words
Ovarian hyperstimulation syndrome/Ascites/Paracentesis/Catheter drainage/In vitro fertilization-embryo transfer分类
医药卫生引用本文复制引用
焦敏洁,段海霞,孙树柳,刘琰,熊莉莉,李小娟..腹腔穿刺置管引流术治疗中重度OHSS患者的妊娠结局分析[J].生殖医学杂志,2025,34(9):1170-1175,6.基金项目
陕西省西安市科技局项目[20YXYJ0005(9)] （9）
