摘要
Abstract
Objective To explore the pathological features and incidence patterns of gastric precancerous lesions,and benign and malignant tumors in the stomach region of a certain region of Tianjin.Methods The pathological diagnosis results of 28110 cases of gastroscopy from a tertiary general hospital in Tianjin from July 2014 to August 2024 were extracted.The features of the disease spec-trum,as well as the lesion sites,pathological type,differentiation degrees,gender,age,etc.of precancerous lesions and gastric canc-er were analyzed.Results The main types of diseases diagnosed by gastroscopy included inflammatory diseases(68.25%),benign tumors and malignant tumors.There were 19186 cases of gastric inflammatory diseases,among which chronic atrophic gastritis accoun-ted for 35.72%(6 854/19 186)and chronic non-atrophic gastritis for 63.46%(12 176/19 186),all of which were more common in the gastric antrum.Among the 7 587 cases of benign tumors,polyps accounted for 93.73%(7 111/7 587).Among the 716 cases of malignant tumors,adenocarcinoma accounted for 72.07%(516/716)and gastrointestinal stromal tumors accounted for 22.77%(163/716).The average age of patients with low and low-to-moderately differentiated adenocarcinoma was 64.00(56.00,71.00)years,while that of patients with moderately and moderately-to-highly differentiated adenocarcinoma was 70.04±9.38 years.The age difference between the two groups was statistically significant(P<0.05).The detection rate of gastric cancer in males was higher than that in fe-males,and the detection rate of low and low-to-moderately differentiated adenocarcinoma was higher than that of moderately and moder-ately-to-highly differentiated adenocarcinoma before the age of 60.Gastric dysplasia was detected in 3,720 cases,with a detection rate of 13.23%(3,720/28,110).The average age of high-grade dysplasia(HGD)was 63.35±10.31,and that of low-grade dysplasia(LGD)was 59.00(51.00,66.00)years.The age difference between the two groups was statistically significant(P<0.05).Intesti-nal metaplasia was detected in 9,922 cases,with a detection rate of 35.30%(9,922/28,110),and the average age was 59.00(51.00,65.00)years.Conclusions Gastric malignant tumors in the area of Tianjin are mainly adenocarcinoma and stromal tumors.It is recom-mended that people in this region,especially males(over 40 years old or earlier),should regularly undergo gastroscopy for early detection and intervention to reduce the incidence.关键词
胃镜/病理/疾病谱/癌前病变/异型增生/肠上皮化生/胃癌Key words
gastroscope/pathology/disease spectrum/precancerous lesion/dysplasia/intestinal metaplasia/gastric cancer分类
医药卫生
