现代医药卫生2025，Vol.41Issue(9)：2039-2043,2048,6.DOI:10.3969/j.issn.1009-5519.2025.09.005
GLP-1受体激动剂对糖尿病肾病的影响
Effect of GLP-1 receptor agonists on diabetic nephropathy
摘要
Abstract
Diabetic nephropathy(DKD)is the main cause of end-stage renal disease.Glucagon-like pep-tide-1(GLP-1)receptor agonists are a new type of hypoglycemic drugs that can improve cardiovascular and renal events in patients with diabetes.This article mainly discussed the classification of GLP-1 receptor ago-nists and the main pathogenesis of DKD,and analyzed the protective effects of GLP-1 receptor agonists on DKD,such as reducing urinary albumin,promoting urinary sodium excretion,regulating lipid metabolism,anti-fibrosis,and improving oxidative stress,renal blood flow,and renal outcomes.关键词
糖尿病肾病/胰高血糖素样肽-1受体激动剂/氧化应激/肾脏结局/综述Key words
Diabetic nephropathy/Glucagon-like peptide-1 receptor agonist/Oxidative stress/Renal outcomes/Review分类
医药卫生引用本文复制引用
石峻岭,尹经霞,廖涌,杨刚毅..GLP-1受体激动剂对糖尿病肾病的影响[J].现代医药卫生,2025,41(9):2039-2043,2048,6.基金项目
重庆市卫生健康委员会中医科研项目(2024WSJK192) （2024WSJK192）
重庆市南岸区科卫联合医学科研项目(2023-03). （2023-03）
