现代医药卫生2025，Vol.41Issue(9)：2058-2062,5.DOI:10.3969/j.issn.1009-5519.2025.09.009
血清维生素D水平与MetALD的相关性研究
Correlation between serum vitamin D level and MetALD
摘要
Abstract
Objective To study the correlation between serum vitamin D[25(OH)D3]level and meta-bolically associated alcoholic liver disease(MetALD).Methods The clinical data of 303 patients who under-went abdominal ultrasound or CT examination in the Affiliated Hospital of Inner Mongolia Minzu University from January 2017 to November 2023 were retrospectively collected.According to whether they were diag-nosed as MetALD,they were divided into the MetALD group(156 cases)and the non-MetALD group(147 cases).The differences in clinical characteristics between the two groups were compared.According to the level of serum 25(OH)D3,the patients were divided into the sufficient group(49 cases),the insufficient group(171 cases)and the deficient group(83 cases).The risk of MetALD was compared among the three groups.Binary logistic regression model was used to analyze the risk factors of MetALD.Results Compared with the non-MetALD group,the proportion of male,young age,hypertension,diabetes,vitamin D deficiency,body mass index,triglyceride,low-density lipoprotein cholesterol,fasting blood glucose,alanine aminotransferase,γ-glutamyl transpeptidase levels in the MetALD group were higher,and the levels of high-density lipoprotein cholesterol and 25(OH)D3 were lower.The proportion of vitamin D insuficient was high,the differences were statistically significant(P<0.05).Vitamin D deficiency,male,overweight/obesity,hypertension,diabetes,hy-pertriglyceridemia,high low-density lipoprotein cholesterol,low high-density lipoprotein cholesterol,high ala-nine aminotransferase,and high γ-glutamyl transpeptidase were risk factors for MetALD(P<0.05).The pa-tients in the insufficient group had a higher risk of disease,and the patients in the lack group had the highest risk of disease,the differences were statistically significant(P<0.05).Conclusion Serum vitamin D deficien-cy is a risk factor for MetALD.The lower the vitamin D level,the higher the risk of disease.关键词
维生素D/代谢和酒精相关脂肪变性肝病/危险因素Key words
Vitamin D/Metabolically associated alcoholic liver disease/Risk factors分类
医药卫生引用本文复制引用
冯帆,杜晓旭,包萨如拉,戈宏焱..血清维生素D水平与MetALD的相关性研究[J].现代医药卫生,2025,41(9):2058-2062,5.基金项目
内蒙古自治区直属高校基本科研业务项目(GXKY23Z044). （GXKY23Z044）
