现代医药卫生2025，Vol.41Issue(9)：2182-2188,2194,8.DOI:10.3969/j.issn.1009-5519.2025.09.035
经皮耳迷走神经电刺激对意识障碍患者促醒的临床研究现状
Clinical research status of percutaneous auricular vagus nerve stimulation in promoting awakening of patients with disorders of consciousness
陈宇 1牛陵川1
作者信息
- 1. 重庆医科大学附属第二医院康复医学科,重庆 400010
- 折叠
摘要
Abstract
In recent years,disorders of consciousness(DoC)caused by severe brain injury or neurologi-cal dysfunction have garnered significant attention within the neuroscience community.Transaural vagus nerve stimulation(taVNS)is an emerging neurostimulation technique in the field of neuroscience and is currently considered a safe and effective method for treating neurological disorders such as epilepsy and depression.Re-cent studies have also indicated that taVNS can improve the level of arousal in comatose patients with trau-matic brain injury.This article reviewed clinical studies on the use of taVNS to promote arousal in patients with brain injury-related DoC from multiple perspectives.First,it analyzed the definition and classification of brain injury-related DoC,explores its complex pathogenesis,and outlines the current treatment landscape for brain injury-related DoC.Second,it explored the mechanism of action of taVNS in treating patients with brain injury-induced DoC,and combines existing relevant clinical studies with commonly used assessment methods in clinical practice to investigate the treatment parameter settings for taVNS in clinical treatment of brain inju-ry-induced DoC,as well as the overall safety and efficacy of clinical research.Finally,it explored the future challenges and prospects of taVNS in promoting the recovery of consciousness,pointed out that the safety,ef-ficacy and long-term efficacy of taVNS still need more support,and emphasized that large-scale randomized controlled trials and mechanism research should be the focus of future research.It is hoped to provide more use-ful references for clinical practice and promote the further exploration of new therapies for DoC in brain injury.关键词
经皮耳迷走神经电刺激/意识障碍/促醒/综述Key words
Percutaneous auricular vagus nerve stimulation/Disorders of consciousness/Promote awakening/Review分类
医药卫生引用本文复制引用
陈宇,牛陵川..经皮耳迷走神经电刺激对意识障碍患者促醒的临床研究现状[J].现代医药卫生,2025,41(9):2182-2188,2194,8.
