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精准微创在腹腔镜保脾胰体尾切除术中的疗效分析

黄鑫 李晓勇 杨雁灵 李晓东 顾昊武 南博 铁静静 张宁 王振华 吴菲菲 王亚云

空军军医大学学报2025,Vol.46Issue(9):1163-1169,7.
空军军医大学学报2025,Vol.46Issue(9):1163-1169,7.DOI:10.13276/j.issn.2097-1656.2025.09.008

精准微创在腹腔镜保脾胰体尾切除术中的疗效分析

Analysis of the efficacy of precision minimally invasive technique in laparoscopic spleen-preserving distal pancreatectomy

黄鑫 1李晓勇 1杨雁灵 2李晓东 2顾昊武 3南博 2铁静静 4张宁 2王振华 2吴菲菲 5王亚云5

作者信息

  • 1. 延安大学附属医院肝胆胰外科,陕西延安 716000
  • 2. 空军军医大学西京医院肝胆外科,陕西西安 710032
  • 3. 解放军西部战区陆军航空兵旅场站,四川成都 610083
  • 4. 延安大学医学院人体解剖与组织胚胎学教研室,陕西延安 716000
  • 5. 空军军医大学基础医学院神经系统疾病线粒体可塑性实验室,国家级基础医学实验教学示范中心,陕西西安 710032
  • 折叠

摘要

Abstract

Objective To comparatively study the clinical efficacy and safety between Kimura and Warshaw procedures in laparoscopic spleen-preserving distal pancreatectomy(LSPDP).Methods A retrospective cohort study design was conducted,involving 102 patients who underwent LSPDP from June 2018 to June 2023,with 62 cases in the Kimura group and 40 cases in the Warshaw group.Perioperative indicators,splenic function preservation,and complications were compared between the two groups.Results The Warshaw group exhibited significantly higher incidence of splenic infarction than the Kimura group(22.5%vs 3.2%,P=0.003),with 3 cases of overwhelming post-splenectomy infection observed.Tuftsin levels at 6 months postoperatively were higher in the Kimura group[(0.82±0.11)mg/L vs(0.71±0.13)mg/L,P=0.002)].The Kimura group demonstrated shorter operative time[(185.6±35.2)min vs(215.4±42.1)min,P=0.012)]and reduced blood loss[(152.8±89.5)mL vs(298.6±120.7)mL,P<0.001)].Multivariate analysis identified type Ⅳ splenic vessels(OR=6.63)and intraoperative blood loss>300 mL(OR=4.77)as independent risk factors for spleen preservation failure.Conclusion The Kimura procedure demonstrates advantages in reducing splenic infarction risk,preserving immune function,and enhancing surgical safety through maintenance of splenic hilar vascular integrity,providing practical evidence for"Functional Spleen Preservation".

关键词

腹腔镜/胰腺切除术/Kimura法/Warshaw法/围手术期并发症/脾梗死/脾门血管/脾切除后凶险性感染

Key words

laparoscopic/pancreatectomy/Kimura's method/Warshaw's method/perioperative complications/splenic infarction/splenic hilar vascular/overwhelming post-splenectomy infection

分类

医药卫生

引用本文复制引用

黄鑫,李晓勇,杨雁灵,李晓东,顾昊武,南博,铁静静,张宁,王振华,吴菲菲,王亚云..精准微创在腹腔镜保脾胰体尾切除术中的疗效分析[J].空军军医大学学报,2025,46(9):1163-1169,7.

基金项目

陕西省自然科学基础研究计划项目(2024JC-ZDXM-60) (2024JC-ZDXM-60)

空军军医大学学报

2097-1656

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