中国康复理论与实践2025，Vol.31Issue(9)：993-999,7.DOI:10.3969/j.issn.1006-9771.2025.09.001
单双侧经颅直流电刺激对卒中后吞咽障碍的效果比较
Effect of unilateral or bilateral transcranial direct current stimulation on post-stroke dysphagia
摘要
Abstract
Objective To investigate the effect of unilateral or bilateral transcranial direct current stimulation(tDCS)on post-stroke dysphagia. Methods From February,2023 to March,2025,27 stroke patients with dysphagia and nasal feeding in Beijing Bo'ai Hos-pital were randomly divided into healthy side stimulation group,bilateral stimulation group and sham stimulation group,with nine cases in each group.All the groups received conventional swallowing training and tDCS,while the healthy side stimulation group stimulated on the healthy side of oropharyngeal cortex;and the bilateral stimu-lation group alternatively stimulated bilateral oropharyngeal cortex,with one hour interval between bilateral stim-ulation;the sham stimulation group stimulated the healthy side of oropharyngeal cortex for 30 seconds and then stop.The course lasted two weeks.The scores of Standard Swallowing Function Assessment Scale(SSA),Modi-fied Mann Assessment of Swallowing Ability(MMASA)and Rosenbek Penetration-Aspiration Scale(PAS)were compared before and after treatment. Results The intra-group effect(F=16.185,P<0.01)was significant in the scores of SSA,the intra-group effect(F=28.650,P<0.01)and interaction effect(F=3.453,P<0.01)were significant in the scores of MMASA,and there was no significant difference in the inter-group effect,intra-group effect and interaction effect in the scores of PAS(P>0.05).Post hoc test showed that there was no significant difference in the scores of SSA,MMASA and PAS among three groups(P>0.05).There was significant difference in the score difference of MMASA be-fore and after treatment among three groups(F=4.698,P<0.05).Post hoc test showed that the score difference of MMAS was more in the healthy side stimulation group than in the bilateral stimulation group and the sham stimulation group(P<0.05),with no significant difference between the bilateral stimulation group and the sham stimulation group(P>0.05). Conclusion tDCS can partly improve post-stroke dysphagia.The healthy side anode stimulation is superior to the alter-nating bilateral hemisphere anode stimulation.关键词
卒中后吞咽障碍/经颅直流电刺激/刺激靶点Key words
post-stroke dysphagia/transcranial direct current stimulation/site分类
医药卫生引用本文复制引用
高飞,刘丽旭,胡雪艳,吴晓莉,杨凌宇,杨宇琦,叶长青,杜晓霞..单双侧经颅直流电刺激对卒中后吞咽障碍的效果比较[J].中国康复理论与实践,2025,31(9):993-999,7.基金项目
中国康复研究中心面上课题(No.2022ZX-21) Supported by China Rehabilitation Research Center Project(General)(No.2022ZX-21) （No.2022ZX-21）
