中国康复理论与实践2025，Vol.31Issue(9)：1057-1065,9.DOI:10.3969/j.issn.1006-9771.2025.09.009
远隔缺血适应联合双耳节拍音乐训练对脑梗死认知障碍的效果
Effect of remote ischemic conditioning combined with binaural beat music training in patients with cognitive dys-function after cerebral infarction
摘要
Abstract
Objective To explore the effect of remote ischemic conditioning(RIC)combined with binaural beat music(BBM)train-ing in patients with cognitive dysfunction after cerebral infarction. Methods From June,2024 to January,2025,200 patients with cognitive dysfunction after cerebral infarction in the Affil-iated Hospital of North China University of Science and Technology were randomly divided into control group(n=50),RIC group(n=50),BBM group(n=50)and combined group(n=50).All the groups received stan-dardized routine training,RIC group received RIC,BBM group received BBM,and the combined group received RIC+BBM,for 14 days.They were assessed with Montreal Cognitive Assessment(MoCA)and Stroke-Specific Quality of Life Scale(SS-QOL)at baseline,day 14,and day 90. Results Two cases in the control group,four in RIC group,three in BBM group and three in the combined group dropped out.For MoCA scores,the inter-group effect,intra-group effect and interaction effect were all significant(F>13.463,P<0.001).After intervention,on both day 14 and day 90,the score of MoCA was higher in each in-tervention group than in the control group(P<0.05),and was higher in the combined group than in both BBM and RIC groups(P<0.05);and on day 90,it was higher in RIC group than in BBM group(P<0.05).For SS-QOL,the score increased with time in all the groups(χ2>75.182,P<0.001).After intervention,there was signif-icant difference at each time point among four groups(H>18.260,P<0.001).On day 14 and day 90,the score of SS-QOL was higher in the combined group than in the control and BBM groups(|Z|>3.149,P<0.05);on day 90,the score was higher in RIC group than in the control group(|Z|=3.590,P<0.05),and it was higher in the combined group than in RIC group(|Z|=3.186,P<0.05). Conclusion RIC,BBM and their combination all improved cognitive function after cerebral infarction.RIC was superior to BBM,and the combined intervention yielded the greatest benefit.Both RIC and the combined intervention im-proved quality of life,with the combined approach being the most effective.关键词
脑梗死/远隔缺血适应/双耳节拍音乐/认知障碍/生活质量Key words
cerebral infarction/remote ischemic conditioning/binaural beat music/cognitive dysfunction/quality of life分类
医药卫生引用本文复制引用
薛星,赵海燕,岳淑玲,成杰,唐启群,成晓华,郭宗海,刘萍萍..远隔缺血适应联合双耳节拍音乐训练对脑梗死认知障碍的效果[J].中国康复理论与实践,2025,31(9):1057-1065,9.基金项目
河北省医学科学研究课题计划项目(No.20242303) Supported by Hebei Province Medical Science Research Planning(No.20242303) （No.20242303）
