中国畜牧杂志2025，Vol.61Issue(10)：9-16,8.DOI:10.19556/j.0258-7033.20250403-05
猪内源抗菌肽的生物学功能、表达特征及其调控研究进展
Research Progress on Biological Functions,Expression Characteristics and Regulation of Porcine Endogenous Antimicrobial Peptides
摘要
Abstract
Antimicrobial peptides,as important component of the innate immune system,have broad-spectrum anti-pathogenic microorganism and immunomodulatory activities.The expression of porcine endogenous antimicrobial peptides exhibits breed differences and spatiotemporal specificity,and is regulated by factors such as nutrients,plant extracts,microorganisms,stress,and functional additives.Existing research indicates that β-defensins have both antibacterial and good stability properties,PR-39 has outstanding tissue repair and immunomodulatory abilities,and PG-1 can significantly inhibit multidrug resistant bacteria and viruses.This article reviewed the structure,biological functions,expression characteristics,and regulatory mechanisms of major porcine endogenous antimicrobial peptides(β-defensins,PR-39,and PG-1),aiming to provide references for the research on expression characteristics and regulation of porcine endogenous antimicrobial peptides.关键词
猪内源抗菌肽/生物学功能/表达特征/品种差异/表达调控/分子机制Key words
Porcine endogenous antimicrobial peptides/Biological functions/Expression characteristics/Breed differences/Expression regulation/Molecular mechanisms分类
农业科技引用本文复制引用
辛烨,谭碧娥,孔祥峰..猪内源抗菌肽的生物学功能、表达特征及其调控研究进展[J].中国畜牧杂志,2025,61(10):9-16,8.基金项目
国家重点研发计划项目课题(2023YFD1301305) （2023YFD1301305）
