中国药理学通报2025，Vol.41Issue(10)：1818-1822,5.DOI:10.12360/CPB202502074
大麻二酚对中枢神经系统疾病的保护作用研究进展
Research progress on protective effect of cannabidiol on central nervous system diseases
摘要
Abstract
Cannabidiol(CBD),a natural,non-toxic,non-psy-choactive cannabinoid extracted from Cannabis sativa L,has a wide range of pharmacological activities,including anti-inflam-matory,antioxidant,immunomodulatory,analgesic,anti-tumor,anti-convulsant,anxiolytic effects.Recent studies have indica-ted that CBD may have potential neuroprotective effects in vari-ous models of central nervous system diseases.This paper re-views the experimental research progress of CBD in central nerv-ous system diseases and its possible neuroprotective mecha-nisms,aiming to provide references for its clinical application and new drug development.关键词
大麻二酚/中枢神经系统疾病/神经保护/研究进展/阿尔茨海默病/帕金森病Key words
cannabidiol/central nervous system diseases/neu-roprotection/research progress/Alzheimer's disease/Parkinson's disease分类
医药卫生引用本文复制引用
李盼盼,王保奇,沈晓明,张杰,许玉珉..大麻二酚对中枢神经系统疾病的保护作用研究进展[J].中国药理学通报,2025,41(10):1818-1822,5.基金项目
国家自然科学基金资助项目(No 81904264,81904265,81303011) （No 81904264,81904265,81303011）
河南省中医药科学研究专项课题(No 2019ZY1006) （No 2019ZY1006）
