中华骨质疏松和骨矿盐疾病杂志2025，Vol.18Issue(4)：489-496,8.DOI:10.3969/j.issn.1674-2591.2025.04.013
乳铁蛋白在骨重塑中的作用
Role of lactoferrin in bone remodelling
摘要
Abstract
Lactoferrin(LF)is a multifunctional protein,a member of the transferrin family,with anti-inflam-matory,antioxidant,and immunological properties.Bone is one of the largest organ systems in the human body and has the role of supporting movement,protection,storage of minerals and regulation of metabolism.Bone is a dynamically active tissue that requires constant remodelling to maintain its normal physiological function.A large number of studies have found that LF has a role in regulating bone remodelling,however,the specific mechanism has not been fully elucida-ted.This article summarizes the structure and function of LF through literature review and elaborates the potential mecha-nism of lactoferrin in regulating bone remodelling,and it provides a theoretical basis for in-depth study of the role of LF on bone remodelling and a new idea for the treatment of bone diseases in clinical practice.关键词
乳铁蛋白/骨形成/骨吸收/骨重塑Key words
lactoferrin/bone formation/bone resorption/bone remodelling分类
医药卫生引用本文复制引用
连纷纷,马誉玮,李慧,周芮,吴伟..乳铁蛋白在骨重塑中的作用[J].中华骨质疏松和骨矿盐疾病杂志,2025,18(4):489-496,8.基金项目
上海市人类运动能力开发与保障重点实验室(上海体育学院)资助项目(11DZ2261100) （上海体育学院）
