中国现代医生2025，Vol.63Issue(25)：24-27,31,5.DOI:10.3969/j.issn.1673-9701.2025.25.006
残余胆固醇对正常LDL-C老年人群颈动脉粥样硬化斑块风险的影响
The impact of remnant cholesterol on the risk of carotid atherosclerotic plaques in elderly individuals with normal LDL-C levels
摘要
Abstract
Objective To explore the effect of remnant cholesterol(RC)levels on carotid atherosclerotic plaque risk in elderly individuals with normal low density lipoprotein cholesterol(LDL-C).Methods A total of 753 elderly individuals with normal LDL-C levels who were examined at Quanzhou Hospital of Traditional Chinese Medicine from March 2017 to January 2023 were included in the study.They were divided into low RC group and high RC group according to the RC levels.Kaplan-Meier risk curves were constructed,and the Cox proportional hazards regression model was used to analyze the risk factors for the occurrence of carotid atherosclerotic plaques.Results During the follow-up period,the risk of plaque occurrence in high RC group was significantly higher than that in low RC group(P＜0.001).Cox proportional hazards regression analysis showed that age,gender,RC levels and glycated hemoglobin were independent influencing factors for carotid atherosclerotic plaque.After comprehensive adjustment for confounding factors,the independent predictive effect of RC levels on the risk of carotid atherosclerotic plaque remained significant.Conclusion Elevated RC increases the risk of carotid artery atherosclerotic plaques in elderly individuals with normal LDL-C levels.关键词
残余胆固醇/低密度脂蛋白胆固醇/颈动脉粥样硬化斑块/动脉粥样硬化性心血管疾病Key words
Remnant cholesterol/Low density lipoprotein cholesterol/Carotid artery atherosclerotic plaques/Atherosclerotic cardiovascular disease分类
医药卫生引用本文复制引用
王雳,吴志阳..残余胆固醇对正常LDL-C老年人群颈动脉粥样硬化斑块风险的影响[J].中国现代医生,2025,63(25):24-27,31,5.基金项目
福建省泉州市科技计划项目(2025QZNG055) （2025QZNG055）
2024年市级中医临床重点专科建设项目(泉卫中医函[2024]269号) （泉卫中医函[2024]269号）
