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健脾益肾法治疗癌症化疗后骨髓抑制疗效的Meta分析

黄文杰 王振强

中医临床研究2025,Vol.17Issue(15):42-47,6.
中医临床研究2025,Vol.17Issue(15):42-47,6.DOI:10.3969/j.issn.1674-7860.2025.15.010

健脾益肾法治疗癌症化疗后骨髓抑制疗效的Meta分析

A Meta-analysis of the effect of invigorating spleen and tonifying kidney therapy on bone marrow suppression after cancer chemotherapy

黄文杰 1王振强2

作者信息

  • 1. 河北中医药大学,河北 石家庄,050000
  • 2. 河北中医药大学附属河北省沧州中西医结合医院,河北 沧州,061000
  • 折叠

摘要

Abstract

Objective:To systematically evaluate the clinical effect of invigorating spleen and tonifying kidney therapy in the treatment of bone marrow suppression after cancer chemotherapy.Methods:All the clinical randomized controlled literatures on the treatment of bone marrow suppression after cancer chemotherapy by invigorating spleen and tonifying kidney therapy in CNKI,Wanfang,VIP,SinoMed,PubMed,Embase and other databases from the establishment of the database to December 2022 were searched by computer.A Meta-analysis was performed using RevMan 5.3 software.Results:Finally,a total of 13 articles were included.The Meta-analysis showed that compared with the control group,the study group could significantly ameliorate the incidence of bone marrow suppression[RR=0.51,95%CI(0.32,0.82),P<0.05],hemoglobin reduction[RR=0.80,95%CI(0.68,0.95),P<0.05],and the incidence of thrombocytopenia[RR=0.69,95%CI(0.59,0.82),P<0.05],the incidence of leukopenia[RR=0.74,95%CI(0.66,0.83),P<0.05].Conclusion:Traditional Chinese medicine based on invigorating spleen and tonifying kidney therapy can improve the hematopoietic function of cancer patients after chemotherapy and reduce the prevalence of bone marrow suppression.Due to the generally low quality of the included literatures,the above conclusions still need more high-quality,multi-center,and large-sample studies for verification.

关键词

健脾益肾疗法/化疗/骨髓抑制/Meta分析

Key words

Invigorating spleen and tonifying kidney therapy/Chemotherapy/Bone marrow suppression/Meta-analysis

分类

医药卫生

引用本文复制引用

黄文杰,王振强..健脾益肾法治疗癌症化疗后骨髓抑制疗效的Meta分析[J].中医临床研究,2025,17(15):42-47,6.

中医临床研究

1674-7860

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