摘要
Abstract
Objective:To systematically evaluate the clinical effect of invigorating spleen and tonifying kidney therapy in the treatment of bone marrow suppression after cancer chemotherapy.Methods:All the clinical randomized controlled literatures on the treatment of bone marrow suppression after cancer chemotherapy by invigorating spleen and tonifying kidney therapy in CNKI,Wanfang,VIP,SinoMed,PubMed,Embase and other databases from the establishment of the database to December 2022 were searched by computer.A Meta-analysis was performed using RevMan 5.3 software.Results:Finally,a total of 13 articles were included.The Meta-analysis showed that compared with the control group,the study group could significantly ameliorate the incidence of bone marrow suppression[RR=0.51,95%CI(0.32,0.82),P<0.05],hemoglobin reduction[RR=0.80,95%CI(0.68,0.95),P<0.05],and the incidence of thrombocytopenia[RR=0.69,95%CI(0.59,0.82),P<0.05],the incidence of leukopenia[RR=0.74,95%CI(0.66,0.83),P<0.05].Conclusion:Traditional Chinese medicine based on invigorating spleen and tonifying kidney therapy can improve the hematopoietic function of cancer patients after chemotherapy and reduce the prevalence of bone marrow suppression.Due to the generally low quality of the included literatures,the above conclusions still need more high-quality,multi-center,and large-sample studies for verification.关键词
健脾益肾疗法/化疗/骨髓抑制/Meta分析Key words
Invigorating spleen and tonifying kidney therapy/Chemotherapy/Bone marrow suppression/Meta-analysis分类
医药卫生