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Structure-based design of covalent nanobody binders for a thermostable green fluorescence protein

Zhihao Yue Yanfang Li Hongmin Cai Hebang Yao Dianfan Li Aimin Ni Tingting Li

Acta Biochimica et Biophysica Sinica2025,Vol.57Issue(8):P.1363-1370,8.
Acta Biochimica et Biophysica Sinica2025,Vol.57Issue(8):P.1363-1370,8.DOI:10.3724/abbs.2024233

Structure-based design of covalent nanobody binders for a thermostable green fluorescence protein

Zhihao Yue 1Yanfang Li 2Hongmin Cai 3Hebang Yao 4Dianfan Li 2Aimin Ni 2Tingting Li2

作者信息

  • 1. Center for Excellence in Molecular Cell Science,Shanghai Institute of Biochemistry and Cell Biology,Chinese Academy of Sciences,Shanghai 200031,China University of Chinese Academy of Sciences,Beijing 100049,China
  • 2. Center for Excellence in Molecular Cell Science,Shanghai Institute of Biochemistry and Cell Biology,Chinese Academy of Sciences,Shanghai 200031,China
  • 3. Center for Excellence in Molecular Cell Science,Shanghai Institute of Biochemistry and Cell Biology,Chinese Academy of Sciences,Shanghai 200031,China State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201210,China
  • 4. Center for Excellence in Molecular Cell Science,Shanghai Institute of Biochemistry and Cell Biology,Chinese Academy of Sciences,Shanghai 200031,China School of Life Science and Technology,ShanghaiTech University,Shanghai 201210,China
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摘要

关键词

disulfide engineering/rational design/synthetic nanobody/thermostable green fluorescence protein

分类

生物科学

引用本文复制引用

Zhihao Yue,Yanfang Li,Hongmin Cai,Hebang Yao,Dianfan Li,Aimin Ni,Tingting Li..Structure-based design of covalent nanobody binders for a thermostable green fluorescence protein[J].Acta Biochimica et Biophysica Sinica,2025,57(8):P.1363-1370,8.

基金项目

supported by the grants from the National Natural Science Foundation of China(Nos.32201000 to T.L.,82151215,and 32471246 to D.L.) (Nos.32201000 to T.L.,82151215,and 32471246 to D.L.)

the Science and Technology Commission of Shanghai Municipality(No.22ZR1468300 to D.L.) (No.22ZR1468300 to D.L.)

the Shanghai Postdoctoral Excellence Program(No.2021378 to T.L.). (No.2021378 to T.L.)

Acta Biochimica et Biophysica Sinica

1672-9145

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