首页|期刊导航|Acta Biochimica et Biophysica Sinica|Knockdown of lncRNA XR_877193.1 suppresses ferroptosis and promotes osteogenic differentiation via the PI3K/AKT signaling pathway in SONFH

Knockdown of lncRNA XR_877193.1 suppresses ferroptosis and promotes osteogenic differentiation via the PI3K/AKT signaling pathway in SONFH

Huixia Yang Ning Ding Shi Qing Yinju Hao Cilin Zhao Kai Wu Guizhong Li Huiping Zhang Shengchao Ma Zhigang Bai Yideng Jiang

Acta Biochimica et Biophysica Sinica2025，Vol.57Issue(8)：P.1350-1362,13.

Acta Biochimica et Biophysica Sinica2025，Vol.57Issue(8)：P.1350-1362,13.DOI:10.3724/abbs.2025014

Knockdown of lncRNA XR_877193.1 suppresses ferroptosis and promotes osteogenic differentiation via the PI3K/AKT signaling pathway in SONFH

Huixia Yang ¹Ning Ding ¹Shi Qing ²Yinju Hao ²Cilin Zhao ³Kai Wu ¹Guizhong Li ¹Huiping Zhang ⁴Shengchao Ma ³Zhigang Bai ⁵Yideng Jiang¹

作者信息

1. NHC Key Laboratory of Metabolic Cardiovascular Diseases Research,Ningxia Medical University,Yinchuan 750004,China Ningxia Key Laboratory of Vascular Injury and Repair Research,Ningxia Medical University,Yinchuan 750004,China School of Basic Medical Sciences,Ningxia Medical University,Yinchuan 750004,China
2. NHC Key Laboratory of Metabolic Cardiovascular Diseases Research,Ningxia Medical University,Yinchuan 750004,China Ningxia Key Laboratory of Vascular Injury and Repair Research,Ningxia Medical University,Yinchuan 750004,China General Hospital of Ningxia Medical University,Yinchuan 750004,China
3. NHC Key Laboratory of Metabolic Cardiovascular Diseases Research,Ningxia Medical University,Yinchuan 750004,China Ningxia Key Laboratory of Vascular Injury and Repair Research,Ningxia Medical University,Yinchuan 750004,China
4. Department of Medical Genetics,Maternal and Child Health of Hunan Province,Changsha 410008,China General Hospital of Ningxia Medical University,Yinchuan 750004,China
5. NHC Key Laboratory of Metabolic Cardiovascular Diseases Research,Ningxia Medical University,Yinchuan 750004,China Ningxia Key Laboratory of Vascular Injury and Repair Research,Ningxia Medical University,Yinchuan 750004,China Department of Orthopedics,People’s Hospital of Ningxia Hui Autonomous Region,Yinchuan 750004,China
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摘要

关键词

steroid-induced osteonecrosis of the femoral head/ferroptosis/lncRNA XR_877193.1/PI3K/AKT signaling pathway

分类

医药卫生

引用本文复制引用

Huixia Yang,Ning Ding,Shi Qing,Yinju Hao,Cilin Zhao,Kai Wu,Guizhong Li,Huiping Zhang,Shengchao Ma,Zhigang Bai,Yideng Jiang..Knockdown of lncRNA XR_877193.1 suppresses ferroptosis and promotes osteogenic differentiation via the PI3K/AKT signaling pathway in SONFH[J].Acta Biochimica et Biophysica Sinica,2025,57(8):P.1350-1362,13.

基金项目

supported by the grants from the National Natural Science Foundation of China(Nos.82060412,82370293 and U21A20343) （Nos.82060412,82370293 and U21A20343）

the Key Research and Development Projects in Ningxia(Nos.2020BFH02001,2021BEG02028,2022BFH02013,2022BEG02054,and 2023BEG02074) （Nos.2020BFH02001,2021BEG02028,2022BFH02013,2022BEG02054,and 2023BEG02074）

the Ningxia Medical University Level Research Project of Key Project(No.XZ2022005). （No.XZ2022005）

Acta Biochimica et Biophysica Sinica

ISSN：1672-9145

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