首页|期刊导航|Marine Life Science & Technology|Insights into the recognition mechanism of shark-derived single-domain antibodies with high affinity and specificity targeting fluoroquinolones

Insights into the recognition mechanism of shark-derived single-domain antibodies with high affinity and specificity targeting fluoroquinolones

Chang Liu Guoqiang Li Yuan Chen Hong Lin Limin Cao Kaiqiang Wang Xiudan Wang Martin FFlajnik Jianxin Sui

Marine Life Science & Technology2025，Vol.7Issue(2)：P.340-351,12.

Marine Life Science & Technology2025，Vol.7Issue(2)：P.340-351,12.DOI:10.1007/s42995-024-00277-3

Insights into the recognition mechanism of shark-derived single-domain antibodies with high affinity and specificity targeting fluoroquinolones

Chang Liu ¹Guoqiang Li ²Yuan Chen ²Hong Lin ²Limin Cao ²Kaiqiang Wang ²Xiudan Wang ²Martin FFlajnik ³Jianxin Sui²

作者信息

1. State Key Laboratory of Marine Food Processing and Safety Control,College of Food Science and Engineering,Ocean University of China,Qingdao 266404,China School of Chemistry,Chemical Engineering and Biotechnology,Nanyang Technological University,Singapore 637457,Singapore
2. State Key Laboratory of Marine Food Processing and Safety Control,College of Food Science and Engineering,Ocean University of China,Qingdao 266404,China
3. School of Medicine,University of Maryland,Baltimore,MD 21201,USA
折叠

摘要

关键词

Shark-derived single-domain antibody/Fluoroquinolones/In silico/Alanine scanning mutagenesis/Binding mechanism

分类

农业科技

引用本文复制引用

Chang Liu,Guoqiang Li,Yuan Chen,Hong Lin,Limin Cao,Kaiqiang Wang,Xiudan Wang,Martin FFlajnik,Jianxin Sui..Insights into the recognition mechanism of shark-derived single-domain antibodies with high affinity and specificity targeting fluoroquinolones[J].Marine Life Science & Technology,2025,7(2):P.340-351,12.

基金项目

supported by the National Natural Science Foundation of China[No.32072308] （）

the Key Research and Development Program of Shandong Province[No.2023CXGC010709]. （）

Marine Life Science & Technology

ISSN：2096-6490

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