结直肠肛门外科2025，Vol.31Issue(4)：343-345,3.DOI:10.19668/j.cnki.issn1674-0491.2025.04.010
[评论]腹膜反折受累作为直肠癌的预后因素:一项前瞻性研究的长期肿瘤学结果
Peritoneal reflection involvement as a prognostic factor in rectal cancer. Long-term oncological outcomes from a prospective study
ALVAREZ-SARRADO E 1FRASSON M 1SANCHO-MURIEL J 1王枭杰2
作者信息
- 2. 福建医科大学附属协和医院结直肠外科 福建 福州 350001
- 折叠
摘要
Abstract
Purpose To assess the relevance of peritoneal refection involvement in long-term oncological outcomes in pa-tients with rectal cancer.Methods Prospective observational study from a specialized colorectal unit that included a con-secutive series of patients undergoing mesorectal excision for rectal cancer.Peritoneal refection(PR)involvement was evaluated on pathological examination using Shepherd's classifcation.Overall survival(OS),disease-free survival(DFS),and local recurrence(LR)were assessed.Results One hundred sixty patients were included in the present analysis.Peri-toneal involvement was present in 28.2％of the 85 tumors above or at the level of PR.There were no diferences in OS,DFS,or LR according to tumor's height location.The 5-year OS,DFS,and LR for tumors involving PR were 58.3％,61.7％,and 30.3％,respectively.Patients with peritoneal involvement had a higher LR rate(P=0.02)and shorter OS(P=0.04).Shepherd's grade 4 peritoneal involvement was an independent risk factor for OS(HR 2.9,95％CI 1.1-9.5,P=0.04)and LR(HR 4.2,95％CI 1.2-16.9,P=0.04).Conclusion After rectal cancer resection,peritoneal involvement is an independent risk factor for local recurrence and poor survival.关键词
直肠癌/腹膜反折/腹膜受累/局部复发/癌症Key words
rectal cancer/peritoneal refection/peritoneal involvement/local recurrence/carcinomatosis分类
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ALVAREZ-SARRADO E,FRASSON M,SANCHO-MURIEL J,王枭杰..[评论]腹膜反折受累作为直肠癌的预后因素:一项前瞻性研究的长期肿瘤学结果[J].结直肠肛门外科,2025,31(4):343-345,3.
