分子影像学杂志2025，Vol.48Issue(9)：1126-1129,4.DOI:10.12122/j.issn.1674-4500.2025.09.11
糖尿病患者颈动脉斑块的18F-NaF摄取量与Triangle分层模型的相关性
Relationship between 18 F-sodium fluoride uptake in carotid plaques of diabetic patients and the Triangle stratification model
摘要
Abstract
Objective To explore the application value of 18F-NaF PET/CT imaging technology in the assessment of carotid plaque vulnerability and risk stratification in diabetic patients.Methods A total of 59 diabetic patients(102 plaques)and 51 non-diabetic patients(83 plaques)with carotid atherosclerosis from Inner Mongolia Autonomous Region People's Hospital from January 2022 to December 2024 were included as the case group and the control group,respectively.The case group was stratified into high-risk(n=36),medium-risk(n=35),and stable groups(n=31)using the Triangle stratification model.The maximum standardized uptake value(SUVmax),mean standardized uptake value(SUVmean),and target-to-background ratio(TBR)of the plaques were detected by PET/CT,and the differences among the groups and their correlations with risk stratification were compared.Results The SUVmax,SUVmean,and TBR in the case group were higher than those in the control group(P<0.05),and they showed a gradient increasing trend with the increase of risk stratification(P<0.05).SUVmax,SUVmean,and TBR were positively correlated with the risk stratification of diabetes(P<0.05).Conclusion 18F-NaF PET/CT can effectively evaluate the vulnerability of carotid plaques in diabetic patients,and the degree is positively correlated with risk stratification,suggesting that early intervention should be strengthened for high-risk patients to prevent acute vascular events.关键词
18F-NaF PET/CT/颈动脉斑块/糖尿病/危险分层Key words
18F-NaF PET/CT/carotid artery plaque/diabetes mellitus/risk stratification引用本文复制引用
刘昭言,欧阳雪晖,高飞,程齐..糖尿病患者颈动脉斑块的18F-NaF摄取量与Triangle分层模型的相关性[J].分子影像学杂志,2025,48(9):1126-1129,4.基金项目
内蒙古自治区卫生健康科技计划项目(202201031) （202201031）
