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单胺类神经递质电化学传感器的研究进展

钟宇 张瑜 康秀芝 孙晶 董成 吴宏伟 李彦钊 李男

分析化学2025,Vol.53Issue(9):1411-1421,11.
分析化学2025,Vol.53Issue(9):1411-1421,11.DOI:10.19756/j.issn.0253-3820.241145

单胺类神经递质电化学传感器的研究进展

Research Progress on Electrochemical Sensors for Monoamine Neurotransmitters

钟宇 1张瑜 2康秀芝 3孙晶 1董成 2吴宏伟 4李彦钊 5李男6

作者信息

  • 1. 锦州医科大学附属第一医院重症医学科,锦州 121000||大连大学环境与化学工程学院,大连 116622
  • 2. 大连大学环境与化学工程学院,大连 116622
  • 3. 荆门市人民医院,荆楚理工学院附属荆门市人民医院,荆门 448000
  • 4. 大连大学软件工程学院,大连 116622||逆时针芯片科技(大连)有限公司,大连 116622
  • 5. 大连大学附属中山医院,大连 116001
  • 6. 锦州医科大学附属第一医院重症医学科,锦州 121000
  • 折叠

摘要

Abstract

Monoamine neurotransmitters mainly include serotonin,dopamine,epinephrine,and norepinephrine.They play an indispensable regulatory role in key physiological activities such as emotion,sleep,and memory within the central nervous system.Precise detection of these neurotransmitters holds great significance in the field of neuroscience research.Detection methods for monoamine neurotransmitters encompass high-performance liquid chromatography,mass spectrometry,capillary electrophoresis,fluorescence spectroscopy,and electrochemical methods,etc.Compared with other methods,electrochemical methods offer advantages such as high sensitivity,good selectivity,low cost,strong portability,convenient operation,and capability for in vivo real-time detection.This article reviewed recent research progress in electrochemical detection of monoamine neurotransmitters,focusing on a retrospective and summary from three aspects:sensor electrode materials,detection of various monoamine neurotransmitters,and in vivo real-time analysis.Furthermore,the future development of electrochemical sensors for monoamine neurotransmitters was prospected.

关键词

单胺类神经递质/电化学传感器/电极材料/活体原位检测/评述

Key words

Monoamine neurotransmitter/Electrochemical sensor/Electrode material/In vivo in situ detection/Review

引用本文复制引用

钟宇,张瑜,康秀芝,孙晶,董成,吴宏伟,李彦钊,李男..单胺类神经递质电化学传感器的研究进展[J].分析化学,2025,53(9):1411-1421,11.

基金项目

大连大学交叉学科项目(Nos.DLUXK-2024-QN-013,DLUXK-2024-ZD-002)和111引智计划项目(No.D23006)资助. Supported by the Dalian University Interdisciplinary Project(Nos.DLUXK-2024-QN-013,DLUXK-2024-ZD-002)and the 111 Talent Introduction Program(No.D23006). (Nos.DLUXK-2024-QN-013,DLUXK-2024-ZD-002)

分析化学

OA北大核心

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