南京大学学报(自然科学版)2025,Vol.61Issue(5):763-771,9.DOI:10.13232/j.cnki.jnju.2025.05.005
基于聚偏二氟乙烯(PVDF)压电薄膜的球面聚焦超声换能器的制备及其在光声成像中的应用
Fabrication of a spherical focusing ultrasonic transducer based on polyvinylidene fluoride(PVDF)piezoelectric thin film and its application in photoacoustic imaging
摘要
Abstract
Photoacoustic imaging technology is a biomedical imaging technology combining the merits of both acoustic imaging and optical imaging.The ultrasonic transducer determines the key imaging performance such as imaging quality and resolution of photoacoustic imaging directly.We developed a spherical focusing ultrasonic transducer based on PVDF(Polyvinlidene Fluoride)piezoelectric film.Experiments showed that the center frequency of the transducer is 15.5 MHz,and the-6 dB bandwidth is 14.89 MHz(96.1%).We applied the ultrasonic transducer to a photoacoustic microscope system and tested the lateral resolution and axial resolution of the photoacoustic microscope by imaging the resolution plate and a singe hair strand example respectively.The experimental results showed that the lateral resolution of the photoacoustic microscope is 125 μm,which is consistent with the theoretical result of 123.5 μm;the axial resolution is 113.6 μm,which accords with the theoretical result of 88 μm.Finally,we applied our self-developed ultrasonic transducer and photoacoustic imcroscope to image the ear of a living mouse,and obtained clear non-invasive image of the blood vessel network in the mouse ear.Our study indicates that the focused ultrasonic transducer based on PVDF film can provide high imaging resolution and quality for photoacoustic microscope,and has good prospects for biomedical applications.关键词
超声换能器/PVDF压电薄膜/球面聚焦/光声成像/光声显微镜Key words
ultrasonic transducer/PVDF piezoelectric thin film/spherical focusing/photoacoustic imaging/photoacoustic microscope分类
通用工业技术引用本文复制引用
张佥钰,陶超,刘晓峻..基于聚偏二氟乙烯(PVDF)压电薄膜的球面聚焦超声换能器的制备及其在光声成像中的应用[J].南京大学学报(自然科学版),2025,61(5):763-771,9.基金项目
国家自然科学基金(12027808,12374436) (12027808,12374436)